Question · asked by 1 review
Vitamin E vs placebo, no placebo or other supplements: Pre‐eclampsia
- Population
- pregnant women receiving vitamin E supplementation or control, living in areas where there is either inadequate dietary intake of vitamin E or where there is presumed adequate intake.
- Intervention
- Vitamin E
- Comparison
- placebo, no placebo or other supplements
- Outcome
- Pre‐eclampsia
Any vitamin E supplementation showed no clear difference in clinical pre‐eclampsia (random‐effects model) compared with placebo, no placebo or other supplements (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Any vitamin E supplementation vs placebo, no placebo or other supplements Clinical pre‐eclampsia (random‐effects model) · pregnant women receiving vitamin E supplementation or control, living in areas where there is either inadequate… Any vitamin E supplementation showed no clear difference in clinical pre‐eclampsia (random‐effects model) compared with placebo, no placebo or other supplements (moderate certainty). Vitamin E supplementation in pregnancy (2015) · Cochrane Headline outcomes only | RR 0.91 [0.79, 1.06] | 14 studies · 20878 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Vitamin E supplementation in pregnancy 2015 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.