Question · asked by 1 review

Vitamin E vs placebo, no placebo or other supplements: Preterm prelabour rupture of membranes

Any vitamin E supplementation showed no clear difference in prelabour rupture of fetal membranes ‐ preterm compared with placebo, no placebo or other supplements (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Any vitamin E supplementation vs placebo, no placebo or other supplements
Prelabour rupture of fetal membranes ‐ preterm · pregnant women receiving vitamin E supplementation or control, living in areas where there is either inadequate…
Any vitamin E supplementation showed no clear difference in prelabour rupture of fetal membranes ‐ preterm compared with placebo, no placebo or other supplements (low certainty).
Vitamin E supplementation in pregnancy (2015) · Cochrane Headline outcomes only
RR 1.27 [0.93, 1.75]5 studies · 1999 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Vitamin E supplementation in pregnancy
2015 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.