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13 questions · 21 findings · 3 reviews

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Prenatal vitamin D level ≤50 nmol/L vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D)

Dental caries · Children aged 2 to 8 years

The review reported a lower odds ratio at maternal prenatal vitamin D ≤50 nmol/L than at ≤35 nmol/L, without a numeric value in the available sources.

1 finding from 1 review

Prenatal vitamin D level ≤35 nmol/L vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D)

Dental caries · Children aged 2 to 8 years

The review reported a slightly higher odds ratio at maternal prenatal vitamin D ≤35 nmol/L than at ≤50 nmol/L, without a numeric value in the available sources.

1 finding from 1 review

Prenatal vitamin D deficiency (low maternal 25(OH)D during pregnancy) vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D)

Dental caries · Children aged 2 to 8 years

The review reported an OR of 1.32 when prenatal vitamin D was measured at 6 to 38 gestational weeks.

2 findings from 1 review

Prenatal vitamin D deficiency (low maternal 25(OH)D during pregnancy) vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D)

Dental caries in children · Infants and children (aged about 2 to 8 years) whose mothers' vitamin D status was assessed during pregnancy

For prenatal vitamin D measured across gestational weeks 6-38, the OR of dental caries was 1.32 (no CI reported); ungraded.

3 findings from 1 review

Prenatal vitamin D deficiency (low maternal 25(OH)D during pregnancy) vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D)

Dental caries in children · Children aged 6 to 8 years whose mothers' prenatal vitamin D status was assessed

In the single study of children aged 6-8 years, the association was not statistically significant (OR 1.07, 95% CI 0.84-1.30); ungraded.

1 finding from 1 review

Prenatal vitamin D deficiency (low maternal 25(OH)D during pregnancy) vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D)

Dental caries in children · Children aged 4 to 6 years whose mothers' prenatal vitamin D status was assessed

Among children aged 4-6 years, prenatal vitamin D deficiency is associated with significantly higher odds of dental caries (OR 1.44, 95% CI 1.32-1.56); ungraded.

1 finding from 1 review

Prenatal vitamin D deficiency (maternal 25(OH)D measured at gestational weeks 24 to 38) vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D)

Dental caries in children · Infants and children (aged about 2 to 8 years) whose mothers' vitamin D status was assessed during pregnancy

For prenatal vitamin D measured across gestational weeks 24-38, the OR of dental caries was 1.30 (no CI reported); ungraded.

1 finding from 1 review

Vitamin D deficiency (serum 25(OH)D < 50 nmol/L) vs Normal vitamin D level (serum 25(OH)D ≥ 50 nmol/L)

Dental caries · Children (<19 years)

Children with vitamin D deficiency had a 22% higher risk of dental caries than those with normal vitamin D levels (unadjusted RR 1.22; ungraded).

5 findings from 1 review
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Vitamin D deficiency (serum 25(OH)D < 50 nmol/L) vs Normal vitamin D level (serum 25(OH)D ≥ 50 nmol/L)

Dental caries · Children with permanent dentition (>12 years)

In children with permanent dentition, vitamin D deficiency was associated with a 28% higher caries risk (RR 1.28; ungraded).

1 finding from 1 review

Vitamin D deficiency (serum 25(OH)D < 50 nmol/L) vs Normal vitamin D level (serum 25(OH)D ≥ 50 nmol/L)

Dental caries · Children with deciduous dentition (<6 years)

In children with deciduous dentition, vitamin D deficiency was associated with a 68% higher caries risk (RR 1.68; ungraded).

1 finding from 1 review

Vitamin D deficiency (serum 25(OH)D < 50 nmol/L) vs Normal vitamin D level (serum 25(OH)D ≥ 50 nmol/L)

Dental caries · Children (mixed dentition; baseline about 8 years)

In children with mixed dentition, vitamin D deficiency was associated with an 8% higher caries risk (RR 1.08; ungraded).

1 finding from 1 review

Prenatal vitamin D deficiency (low maternal 25(OH)D during pregnancy) vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D)

Dental caries prevalence · Children aged 2 to 8 years

The review reported 44% dental caries prevalence among children of mothers with low prenatal vitamin D.

2 findings from 1 review