Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

780 questions · 834 findings · 76 reviews

No studies found 187 · 22.4%GRADE not reported 164 · 19.7%Very low 144 · 17.3%Low 172 · 20.6%Moderate 105 · 12.6%High 62 · 7.4%

Vitamin D plus calcium vs placebo or control

Hip Fracture · post‐menopausal women and older people at risk of osteoporotic fractures

Vitamin D [D2, D3 or 25(OH)D] plus calcium leads to lower persons sustaining new hip fracture (1 year estimate) compared with control or placebo (high certainty).

1 finding from 1 review

Vitamin D plus calcium vs placebo or control

New fractures · post‐menopausal women and older people at risk of osteoporotic fractures

Vitamin D [D2, D3 or 25(OH)D] plus calcium leads to lower persons sustaining any new fracture (1 year estimate) compared with control or placebo (high certainty).

1 finding from 1 review

Vitamin D plus calcium vs placebo

Adverse events: serum calcium above normal · relatively healthy postmenopausal women

Vitamin D plus calcium showed no clear difference in adverse events: serum calcium above normal compared with placebo (low certainty).

1 finding from 1 review

Steroid plus vitamin D vs steroids

Number of participants achieving 'response' by PGA · scalp psoriasis

Steroid plus vitamin D leads to higher number of participants achieving 'response' by PGA compared with steroid (high certainty).

1 finding from 1 review

Steroid plus vitamin D vs steroids

Number of participants achieving 'clearance' by IGA · scalp psoriasis

Steroid plus vitamin D probably leads to higher number of participants achieving 'clearance' by IGA compared with steroid (moderate certainty).

1 finding from 1 review

Steroid plus vitamin D vs steroids

Number of participants achieving 'response' by IGA · scalp psoriasis

Steroid plus vitamin D probably leads to higher number of participants achieving 'response' by IGA compared with steroid (moderate certainty).

1 finding from 1 review