Neurological functionNo. of participants: 544(3 RCTs) · patients with newly diagnosed multiple brain metastases
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Quality of lifeNo. of participants: 271(2 RCTs) · patients with newly diagnosed multiple brain metastases
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
NON ‐ Healing (persistence or recurrence) · people with anal fissures
Any Surgery leads to lower NON ‐ Healing (persistence or recurrence) compared with any Medical Therapy (high certainty).
1 finding from 1 review
Survival (overall and disease‐ specific) · women with stage IIIc or IV ovarian cancer
It is very uncertain whether ultra‐radical (extensive) surgery changes survival (overall and disease‐ specific) compared with standard surgery (very low certainty).
1 finding from 1 review
Progression‐free survival · women with stage IIIc or IV ovarian cancer
It is very uncertain whether ultra‐radical (extensive) surgery changes progression‐free survival compared with standard surgery (very low certainty).
1 finding from 1 review
Disease-free survival · women with stage IIIc or IV ovarian cancer
It is very uncertain whether ultra‐radical (extensive) surgery changes disease‐free survival compared with standard surgery (very low certainty).
1 finding from 1 review
Rate of optimal cytoreduction · women with stage IIIc or IV ovarian cancer
1 finding from 1 review
no estimate extracted
Studies not reported
High
Recurrence · women with stage IIIc or IV ovarian cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
(Loco)regional control · women with stage IIIc or IV ovarian cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Perioperative mortality · women with stage IIIc or IV ovarian cancer
It is very uncertain whether ultra‐radical (extensive) surgery changes adverse event: perioperative mortality compared with standard surgery (very low certainty).
1 finding from 1 review
Adverse event: serious postoperative morbidity · women with stage IIIc or IV ovarian cancer
It is very uncertain whether ultra‐radical (extensive) surgery changes adverse event: serious postoperative morbidity compared with standard surgery (very low certainty).
1 finding from 1 review
Quality of life · women with stage IIIc or IV ovarian cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · women with operable primary breast cancer
No axillary surgery showed no clear difference in all‐cause mortality compared with full axillary surgery (moderate certainty).
1 finding from 1 review
Locoregional recurrence · women with operable primary breast cancer
No axillary surgery probably leads to higher locoregional recurrence compared with full axillary surgery (moderate certainty).
1 finding from 1 review
Lymphoedema Increase in arm circumference · women with operable primary breast cancer
No axillary surgery may leads to lower lymphoedema Increase in arm circumference compared with full axillary surgery (low certainty).
1 finding from 1 review
Arm or shoulder movement impairment · women with operable primary breast cancer
It is very uncertain whether no axillary surgery changes arm or shoulder movement impairment compared with full axillary surgery (very low certainty).
1 finding from 1 review
Difference in mean IOP from baseline at < 6 months · patients with eyes with cataract and glaucoma
Combined surgery showed no clear difference in mean change in IOP Measured by Goldmann applanation compared with phacoemulsification alone (low certainty).
1 finding from 1 review
Mean change in medications Measured by number of bottles · patients with eyes with cataract and glaucoma
Combined surgery showed no clear difference in mean change in medications Measured by number of bottles compared with phacoemulsification alone (low certainty).
1 finding from 1 review
Need for additional surgery: proportion of participants who received additional surgery to control IOP at 1 year · patients with eyes with cataract and glaucoma
Combined surgery showed no clear difference in proportion who received re‐operation to control IOP within one year… compared with phacoemulsification alone (low certainty).
1 finding from 1 review
Proportion who received intervention for surgical complications within one year Number of participants · patients with eyes with cataract and glaucoma
Combined surgery showed no clear difference in proportion who received intervention for surgical complications… compared with phacoemulsification alone (low certainty).
1 finding from 1 review