Cochrane · systematic review · CD003431
Non surgical therapy for anal fissure
Nelson, RL, Thomas, K, Morgan, J, et al. · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library
ColorectalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
2
current version
GRADE rated
2
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 0 · 0%High 1 · 50%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
GTN versus Placebo for anal fissure
Population: patients with anal fissure
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
NON ‐ Healing of fissure (persistence or recurrence) GTN vs Placebo | OR 0.35 [0.19, 0.65] | 18 studies · 1315 participants | Low |
Any Surgery compared to any Medical Therapy for anal fissure
Population: patients with anal fissure
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
NON ‐ Healing (persistence or recurrence) Any Surgery vs any Medical Therapy | OR 0.11 [0.06, 0.23] | 15 studies · 979 participants | High |