Findings

What do systematic reviews say?

12 questions · 12 findings · 7 reviews

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No studies found 2 · 16.7%GRADE not reported 0 · 0%Very low 8 · 66.7%Low 2 · 16.7%Moderate 0 · 0%High 0 · 0%

Surgery vs no surgery

SAEs · participants with obesity

1 finding from 1 review

Surgery for weight loss in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 438 participants
Very low

Surgery vs non‐surgical treatment

Serious adverse events · people with full‐thickness rotator cuff tears

1 finding from 1 review

Surgery for rotator cuff tears 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Surgery vs radiofrequency ablation

Serious adverse events (number of events) · people with early‐ or very early‐stage hepatocellular carcinoma eligible for surgery

Surgery may leads to higher serious adverse events (number of events) compared with radiofrequency ablation (low certainty).

1 finding from 1 review

Management of people with early‐ or very early‐stage hepatocellular carcinoma 2017 · Cochrane Headline outcomes only
Rate ratio 7.02 [2.29, 21.46]
2 studies · 391 participants
Low

Surgery vs radiofrequency ablation

Serious adverse events (number of participants) · people with early‐ or very early‐stage hepatocellular carcinoma eligible for surgery

Surgery may leads to higher serious adverse events (number of participants) compared with radiofrequency ablation (low certainty).

1 finding from 1 review

Management of people with early‐ or very early‐stage hepatocellular carcinoma 2017 · Cochrane Headline outcomes only
OR 17.96 [2.28, 141.6]
1 study · 120 participants
Low

Day‐surgery vs overnight stay surgery

Serious adverse events · patients with laparoscopic cholecystectomy.

It is very uncertain whether day‐surgery changes serious adverse events compared with overnight stay surgery (very low certainty).

1 finding from 1 review

Day‐surgery versus overnight stay surgery for laparoscopic cholecystectomy 2013 · Cochrane Headline outcomes only
Rate Ratio 3.24 [0.74, 14.09]
4 studies · 391 participants
Very low

Prophylactic plasma transfusion before surgery/invasive procedures vs no prophylactic plasma transfusion before surgery/invasive procedures (colloid, crystalloid, placebo, or no treatment)

Serious adverse events measured by surgery or procedure‐related complications within 30 days ‐ not reported · patients undergoing non‐cardiac surgery/invasive procedures

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic plasma transfusion for patients without inherited bleeding disorders or anticoagulant use undergoing… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prophylactic platelet transfusion prior to surgery vs no prophylactic platelet transfusion prior to surgery

Serious adverse events (surgery‐related adverse effects within 30 days) · people with a low platelet count

1 finding from 1 review

Prophylactic platelet transfusions prior to surgery for people with a low platelet count 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 64 participants
Very low

Prophylactic plasma transfusion before surgery/invasive procedures vs alternative haemostatic agents

Serious adverse events measured by surgery or procedure‐related complications within 30 days ‐ not reported · patients undergoing non‐cardiac surgery/invasive procedures

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic plasma transfusion for patients without inherited bleeding disorders or anticoagulant use undergoing… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prophylactic plasma transfusion before surgery/invasive procedures vs no prophylactic plasma transfusion before surgery/invasive procedures (colloid, crystalloid, placebo, or no treatment)

Serious adverse events measured by plasma transfusion‐related complications within 24 hours № of participants: 21 (1 RCT) · patients undergoing non‐cardiac surgery/invasive procedures

1 finding from 1 review

Prophylactic plasma transfusion for patients without inherited bleeding disorders or anticoagulant use undergoing… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Prophylactic plasma transfusion before surgery/invasive procedures vs alternative haemostatic agents

Serious adverse events measured by plasma transfusion‐related complications within 24 hours № of participants: 21 (1 RCT) · patients undergoing non‐cardiac surgery/invasive procedures

It is very uncertain whether prophylactic plasma transfusion before surgery/invasive procedures changes serious adverse events measured by plasma transfusion‐related… compared with alternative haemostatic agents (very low certainty).

1 finding from 1 review

Prophylactic plasma transfusion for patients without inherited bleeding disorders or anticoagulant use undergoing… 2019 · Cochrane Headline outcomes only
RR 9.82 [0.59, 162.24]
Studies not reported
Very low

Summary of findings. Surgery (percutaneous wire fixation) vs not surgery (cast only)

Serious adverse events (typically more serious complications) ( · children with displaced distal radius fracture with intact or involved or displaced ulna fracture (both‐bone fracture)

It is very uncertain whether summary of findings. Surgery (percutaneous wire fixation) changes serious adverse events (typically more serious complications) ( compared with not surgery (cast only) (very low certainty).

1 finding from 1 review

Interventions for treating wrist fractures in children 2018 · Cochrane Headline outcomes only
RR 0.68 [0.45, 1.02]
4 studies · 253 participants
Very low

Prophylactic platelet transfusion prior to surgery vs alternative treatment

Serious adverse events (transfusion‐related adverse effects within 24 hours of the transfusion) · people with a low platelet count

It is very uncertain whether prophylactic platelet transfusion prior to surgery changes serious adverse events (transfusion‐related adverse effects within… compared with alternative treatments (very low certainty).

1 finding from 1 review

Prophylactic platelet transfusions prior to surgery for people with a low platelet count 2018 · Cochrane Headline outcomes only
RR 2.7 [0.12, 62.17]
1 study · 36 participants
Very low