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Evidence found and GRADE certainty

336 questions · 381 findings · 29 reviews

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No studies found 65 · 17.1%GRADE not reported 28 · 7.3%Very low 117 · 30.7%Low 100 · 26.2%Moderate 54 · 14.2%High 17 · 4.5%

Summary of findings table ‐ Early developmental intervention programmes vs standard follow‐up

Cognitive outcome · preterm infants
3 findings from 1 review

Summary of findings table ‐ Early developmental intervention programmes vs standard follow‐up

Motor outcome at school age (Griffiths Locomotor, MABC) · preterm infants
2 findings from 1 review

Summary of findings table ‐ Promotion/universal prevention interventions vs control group

Diagnosis of mental disorders at study endpoint · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Promotion/universal prevention interventions vs control group

QoL · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Promotion/universal prevention interventions vs control group

Adverse events at study endpoint · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Promotion/universal prevention interventions vs control group

Psychological functioning and impairment at study endpoint (higher score = higher disability) · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Promotion/universal prevention interventions vs control group

Depressive symptoms · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Promotion/universal prevention interventions vs control group

Anxiety · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Promotion/universal prevention interventions vs control group

Distress/PTSD symptoms at study endpoint (higher score = higher severity) · preventing mental disorders
2 findings from 1 review

Summary of findings table (subcomparison 3): chemotherapy agent(s) plus control intervention vs control intervention

Overall survival · palliative participants with esophageal and GE‐junction carcinoma

Summary of findings table (subcomparison 3): chemotherapy agent(s)… probably leads to lower overall survival compared with control intervention alone (moderate certainty).

1 finding from 1 review

Summary of findings table (subcomparison 3): chemotherapy agent(s) plus control intervention vs control intervention

Toxicity · palliative participants with esophageal and GE‐junction carcinoma

It is very uncertain whether summary of findings table (subcomparison 3): chemotherapy agent(s)… changes toxicity compared with control intervention alone (very low certainty).

1 finding from 1 review

Summary of findings table (subcomparison 4): targeted therapy agent plus control intervention vs control intervention

Overall survival · palliative participants with esophageal and GE‐junction carcinoma

Summary of findings table (subcomparison 4): targeted therapy agent… leads to lower overall survival compared with control intervention alone (high certainty).

1 finding from 1 review