Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

110 questions · 119 findings · 11 reviews

No studies found 20 · 16.8%GRADE not reported 11 · 9.2%Very low 62 · 52.1%Low 21 · 17.6%Moderate 2 · 1.7%High 3 · 2.5%

Pharmacological interventions vs placebo

Adverse events (control ‐ placebo) · young people
3 findings from 1 review

Pharmacological interventions vs placebo

Incidence of depression ‐ short‐term: < 6 months · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes incidence of depression ‐ short‐term: < 6 months compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Incidence of depression ‐ medium term: 6‐12 months · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes incidence of depression ‐ medium‐term: 6‐12 months compared with placebo (very low certainty).

1 finding from 1 review

Antidepressants vs placebo

Depression: meeting study criteria for depression at end of · people with stroke

It is very uncertain whether pharmacological interventions (antidepressants) changes depression: meeting study criteria for depression at end treatment… compared with placebo (very low certainty).

1 finding from 1 review

Antidepressants vs placebo

Adverse events: death ‐ at end of treatment (Analysis 1.14) · people with stroke

It is very uncertain whether pharmacological interventions (antidepressants) changes adverse events: death ‐ at end of treatment Analysis 1.12 compared with placebo (very low certainty).

1 finding from 1 review

Adverse effects of pharmacological intervention vs control

Breath holding · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide

It is very uncertain whether adverse effects of pharmacological intervention changes breath holding compared with control (very low certainty).

1 finding from 1 review

Adverse effects of pharmacological intervention vs control

Chest tightness · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide

It is very uncertain whether adverse effects of pharmacological intervention changes chest tightness compared with control (very low certainty).

1 finding from 1 review

Adverse effects of pharmacological intervention vs control

Cough · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide

Adverse effects of pharmacological intervention may leads to higher cough compared with control (low certainty).

1 finding from 1 review

Adverse effects of pharmacological intervention vs control

Adverse effects: pain on injection (solution deposition), Heft-Parker VAS 0-170 mm · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide

Adverse effects of pharmacological intervention showed no clear difference in pain on injection compared with control (low certainty).

1 finding from 1 review