Lacunar stroke · adults
Individuals with periodontitis had about five times higher odds of lacunar stroke than those without periodontitis (pooled OR 5.16); ungraded cross-sectional evidence, with the caution that the three studies came from one research team.
1 finding from 1 review
OR 5.16 [3.68, 7.24]
3 studies
GRADE not reported
Dental caries prevalence · adults
With a non-standard periodontitis definition, the association persisted (OR 1.38).
12 findings from 1 review
Show 9 more findings
Mean DMFT (decayed, missing, filled teeth) · adults
Patients with periodontitis had a non-significantly higher mean DMFT (WMD 0.87).
1 finding from 1 review
Dental caries: prevalence of root caries · adults
Periodontitis was associated with higher root caries odds (OR 2.10).
1 finding from 1 review
Mixed-type caries (crown and root) · adults
One study reported markedly higher mixed-type caries odds with periodontitis (OR 3.40).
1 finding from 1 review
High salivary P. gingivalis (over 10^4 CFU/ml) · adults
Periodontitis was associated with higher odds of detectable high-level salivary P. gingivalis (OR 3.38).
1 finding from 1 review
OR 3.38 [1.46, 7.83]
2 studies
GRADE not reported
High salivary S. mutans (over 10^4 CFU/ml) · adults
Salivary S. mutans showed a non-significant declining trend with periodontitis (OR 0.82).
1 finding from 1 review
OR 0.82 [0.44, 1.51]
2 studies
GRADE not reported
Mean DFR (decayed, filled root teeth) · adults
Patients with periodontitis had a significantly higher mean DFR (WMD 1.13).
1 finding from 1 review
Crown caries · adults
Periodontitis was associated with a small increase in crown caries odds (OR 1.03).
1 finding from 1 review
Lacunar stroke · European-ancestry adults
Genetically predicted periodontitis was associated with modestly higher odds of lacunar stroke (OR 1.24); ungraded MR, though the FDR-adjusted P was 0.064 for the primary IVW-FE method (ML-adjusted P 0.037).
1 finding from 1 review
OR 1.24 [1.03, 1.49]
Studies not reported
GRADE not reported
Malignant transformation (oral cancer development) · Adults in case-control studies of oral cancer; people assessed for periodontitis
Periodontitis is associated with roughly a threefold higher odds of oral cancer (pooled OR 2.94, 95% CI 2.13-4.07; low certainty of evidence), though heterogeneity is moderate (I2=52.4%).
1 finding from 1 review
Root caries (presence of root caries) · Adults (mean age ~53 years)
Adults with periodontal disease had significantly higher odds of root caries than those without (pooled OR 1.38, 95% CI 1.25 to 1.53; 2 observational studies; low certainty).
1 finding from 1 review