Periodontitis vs No periodontitis (periodontal health or gingivitis): Lacunar stroke
- Population
- adults
- Intervention
- Periodontitis
- Comparison
- No periodontitis (periodontal health or gingivitis)
- Outcome
- Lacunar stroke
Individuals with periodontitis had about five times higher odds of lacunar stroke than those without periodontitis (pooled OR 5.16); ungraded cross-sectional evidence, with the caution that the three studies came from one research team.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Periodontitis vs Without periodontitis Lacunar stroke · Adults · Clinical (Japan and Republic of Chile) Individuals with periodontitis had about five times higher odds of lacunar stroke than those without periodontitis (pooled OR 5.16); ungraded cross-sectional evidence, with the caution that the three studies came from one research team. The contribution of oral infectious diseases in lacunar stroke based on meta-analysis and Mendelian… (2025) All outcomes | OR 5.16 [3.68, 7.24] | 3 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| The contribution of oral infectious diseases in lacunar stroke based on meta-analysis and Mendelian randomization study. 2025 All outcomes | August 2024 | 10 | Not applicable |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.