Oral misoprostol 20 µg hourly titrated showed no clear difference in vaginal birth within 24 hours compared with oral misoprostol 25 µg two‐hourly static (low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes caesarean section compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes uterine hyperstimulation with FHR changes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes oxytocin augmentation compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes uterine hyperstimulation without FHR changes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes apgar score less than 7 at 5 minutes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes admission to NICU compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
Sublingual misoprostol alone showed no clear difference in failure to achieve complete abortion compared with vaginal misoprostol alone (low certainty).
Sublingual misoprostol alone showed no clear difference in nausea compared with vaginal misoprostol alone (low certainty).
Sublingual misoprostol alone may leads to lower women's dissatisfaction with the procedure compared with vaginal misoprostol alone (low certainty).
It is very uncertain whether sublingual misoprostol alone changes blood transfusion compared with vaginal misoprostol alone (very low certainty).
Vaginal misoprostol may leads to higher complete miscarriage compared with placebo (low certainty).
Vaginal misoprostol may leads to higher nausea compared with surgical evacuation of uterus (low certainty).
Vaginal misoprostol may leads to higher diarrhoea compared with surgical evacuation of uterus (low certainty).
Vaginal misoprostol may leads to higher pain relief compared with surgical evacuation of uterus (low certainty).
Vaginal misoprostol showed no clear difference in woman’s satisfaction/acceptability of method compared with surgical evacuation of uterus (low certainty).
The review found no eligible studies for this question.
Vaginal misoprostol showed no clear difference in nausea compared with placebo (low certainty).