Adverse events (any type) and safety of sealant · patients with myocardial infarction
It is very uncertain whether lidocaine changes safety (AEs; adverse drug reaction): any adverse event compared with pirmenol (very low certainty).
1 finding from 1 review
Adverse events (AEs; adverse drug reaction): sinus bradycardia · patients with acute myocardial infarction
It is very uncertain whether lidocaine changes adverse events (AEs; adverse drug reaction): sinus bradycardia compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Adverse events (AEs; adverse drug reaction): drowsiness/dizziness · patients with acute myocardial infarction
Lidocaine may leads to higher adverse events (AEs; adverse drug reaction): drowsiness/dizziness compared with placebo or no intervention (low certainty).
1 finding from 1 review
All‐cause mortality · patients with myocardial infarction
It is very uncertain whether lidocaine changes all‐cause mortality compared with disopyramide (very low certainty).
1 finding from 1 review
Cardiac mortality · patients with myocardial infarction
It is very uncertain whether lidocaine changes cardiac mortality compared with disopyramide (very low certainty).
1 finding from 1 review
Injection site pain · Patients requiring local anaesthesia
1 finding from 1 review
Personal preference · Patients requiring local anaesthesia
Plain lidocaine leads to higher preference compared with buffered lidocaine (high certainty).
1 finding from 1 review
Adverse events · Patients requiring local anaesthesia
1 finding from 1 review
Adverse events (e.g. the number of participants that died, or had arrhythmias, other heart rate disorders, or showed any signs of lidocaine toxicity) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Adverse events (e.g. the number of participants that died, or had arrhythmias, other heart rate disorders, or showed any signs of lidocaine toxicity) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Pain with dilation (10 mL 2% lidocaine)a,b · people requesting a surgical abortion at 13+6 weeks' gestation or less (Chin 2020 included people experiencing an early pregnancy loss)
1 finding from 1 review
Pain with dilation (20 mL 1% lidocaine)d,e · people requesting a surgical abortion at 13+6 weeks' gestation or less (Chin 2020 included people experiencing an early pregnancy loss)
1 finding from 1 review
Pain with aspiration (lidocaine)a,b · people requesting a surgical abortion at 13+6 weeks' gestation or less (Chin 2020 included people experiencing an early pregnancy loss)
1 finding from 1 review
Pain with aspiration (20 mL 1% lidocaine)d,e · people requesting a surgical abortion at 13+6 weeks' gestation or less (Chin 2020 included people experiencing an early pregnancy loss)
1 finding from 1 review
Presence of any TNS –lidocaine vs bupivacaine · adults undergoing surgery
Risk of transient neurological symptoms with spinal lidocaine probably leads to lower presence of any TNS –lidocaine vs bupivacaine compared with other local anaesthetic (moderate certainty).
1 finding from 1 review
Presence of any TNS – lidocaine vs 2‐chloroprocaine · adults undergoing surgery
Risk of transient neurological symptoms with spinal lidocaine showed no clear difference in presence of any TNS – lidocaine vs 2‐chloroprocaine compared with other local anaesthetic (low certainty).
1 finding from 1 review
Presence of any TNS – lidocaine vs levobupivacaine · adults undergoing surgery
Risk of transient neurological symptoms with spinal lidocaine may leads to lower presence of any TNS – lidocaine vs levobupivacaine compared with other local anaesthetic (low certainty).
1 finding from 1 review
Presence of any TNS – lidocaine vs mepivacaine · adults undergoing surgery
It is very uncertain whether risk of transient neurological symptoms with spinal lidocaine changes presence of any TNS – lidocaine vs mepivacaine compared with other local anaesthetic (very low certainty).
1 finding from 1 review
Presence of any TNS – lidocaine vs prilocaine · adults undergoing surgery
Risk of transient neurological symptoms with spinal lidocaine probably leads to lower presence of any TNS – lidocaine vs prilocaine compared with other local anaesthetic (moderate certainty).
1 finding from 1 review
Presence of any TNS – lidocaine vs procaine · adults undergoing surgery
Risk of transient neurological symptoms with spinal lidocaine probably leads to lower presence of any TNS – lidocaine vs procaine compared with other local anaesthetic (moderate certainty).
1 finding from 1 review