Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

242 questions · 251 findings · 27 reviews

No studies found 44 · 17.5%GRADE not reported 3 · 1.2%Very low 69 · 27.5%Low 70 · 27.9%Moderate 52 · 20.7%High 13 · 5.2%

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Dinoprostone (prostaglandin E2 analogue) · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in dinoprostone (prostaglandin E2 analogue) compared with placebo or no treatment (low certainty).

1 finding from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Taking adherence · solid organ transplant recipients

Interventions for increasing immunosuppressant medication adherence showed no clear difference in taking adherence compared with standard care (low certainty).

1 finding from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Dosing adherence · solid organ transplant recipients

Interventions for increasing immunosuppressant medication adherence may leads to higher dosing adherence compared with standard care (low certainty).

1 finding from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Timing adherence · solid organ transplant recipients

Interventions for increasing immunosuppressant medication adherence showed no clear difference in timing adherence compared with standard care (low certainty).

1 finding from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Drug holidays · solid organ transplant recipients

Interventions for increasing immunosuppressant medication adherence showed no clear difference in drug holidays compared with standard care (low certainty).

1 finding from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Adherence · solid organ transplant recipients

It is very uncertain whether interventions for increasing immunosuppressant medication adherence changes self‐reported adherence (proportion) compared with standard care (very low certainty).

2 findings from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Proportion of immunosuppressant trough concentration levels at target · solid organ transplant recipients

It is very uncertain whether interventions for increasing immunosuppressant medication adherence changes proportion of immunosuppressant trough concentration levels at target compared with standard care (very low certainty).

1 finding from 1 review

Non‐pharmacological interventions for fear of childbirth (tocophobia) vs usual care

Birth preferences: prefer caesarean section · women with fear of childbirth (tocophobia)

Non‐pharmacological interventions for fear of childbirth (tocophobia) showed no clear difference in birth preferences: prefer caesarean section compared with usual care (low certainty).

1 finding from 1 review

Non‐pharmacological interventions for fear of childbirth (tocophobia) vs usual care

Epidural analgesia during labour · women with fear of childbirth (tocophobia)

Non‐pharmacological interventions for fear of childbirth (tocophobia) showed no clear difference in epidural analgesia during labour compared with usual care (low certainty).

1 finding from 1 review

Self‐management interventions vs usual care

Respiratory‐related hospital admissions · patients with chronic obstructive pulmonary disease

Self‐management interventions including action plans for exacerbations probably leads to lower respiratory‐related hospital admissions compared with usual care (moderate certainty).

1 finding from 1 review · compare the 2 reviews

Self‐management interventions vs usual care

Hospital admissions · patients with chronic obstructive pulmonary disease

Self‐management interventions including action plans for exacerbations showed no clear difference in all‐cause hospital admissions compared with usual care (moderate certainty).

1 finding from 1 review · compare the 2 reviews

Self‐management interventions vs usual care

All‐cause mortality · patients with chronic obstructive pulmonary disease

Self‐management interventions including action plans for exacerbations showed no clear difference in all‐cause mortality compared with usual care (moderate certainty).

1 finding from 1 review · compare the 2 reviews

Self‐management interventions vs usual care

Respiratory‐related mortality · patients with chronic obstructive pulmonary disease

It is very uncertain whether self‐management interventions including action plans for exacerbations changes respiratory‐related mortality compared with usual care (very low certainty).

1 finding from 1 review · compare the 2 reviews