Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,183 questions · 2,385 findings · 241 reviews

No studies found 558 · 23.4%GRADE not reported 158 · 6.6%Very low 704 · 29.5%Low 618 · 25.9%Moderate 276 · 11.6%High 71 · 3%

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs conservative interventions

DASH questionnaire (0 (best function) to 100 (worst function)) ‐ at 1 year · adults with acute acromioclavicular dislocation of the shouldera
1 finding from 1 review

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs conservative interventions

Pain: presence of pain (slight or moderate) at 1 year · adults with acute acromioclavicular dislocation of the shouldera

It is very uncertain whether surgical intervention changes pain: presence of pain (slight or moderate) at 1 year compared with conservative intervention (very low certainty).

1 finding from 1 review

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs conservative interventions

Treatment failure requiring re‐intervention · adults with acute acromioclavicular dislocation of the shouldera

It is very uncertain whether surgical intervention changes treatment failure (usually requiring a subsequent operation) at 1 year compared with conservative intervention (very low certainty).

1 finding from 1 review

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs conservative interventions

Number of participants to return to work/sport ‐ at 1 year · adults with acute acromioclavicular dislocation of the shouldera

Surgical intervention showed no clear difference in number of participants to return to work/sport ‐ at 1 year compared with conservative intervention (low certainty).

1 finding from 1 review

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs conservative interventions

Health‐related quality of life (physical) · adults with acute acromioclavicular dislocation of the shouldera
1 finding from 1 review

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs conservative interventions

Participants with adverse events at 1 year · adults with acute acromioclavicular dislocation of the shouldera

It is very uncertain whether surgical intervention changes participants with adverse events at 1 year compared with conservative intervention (very low certainty).

1 finding from 1 review

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs conservative interventions

Patient dissatisfaction with the cosmetic result at 1 yearh · adults with acute acromioclavicular dislocation of the shouldera

It is very uncertain whether surgical intervention changes patient dissatisfaction with the cosmetic result at 1 yearh compared with conservative intervention (very low certainty).

1 finding from 1 review

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs non‐surgical treatment

Quality of life · Adults with symptomatic mild to moderate knee osteoarthritis defined as knee pain and radiographic evidence of non‐end stage…

The review found no eligible studies for this question.

1 finding from 1 review

Skin care intervention vs standard skin care or no skin care intervention

IgE‐mediated food allergy (oral food challenge) by 1 to 3 years · infants

Skin care intervention showed no clear difference in igE‐mediated food allergy (oral food challenge) by 1 to 3 years compared with standard skin care or no skin care intervention (low certainty).

1 finding from 1 review

Skin care intervention vs standard skin care or no skin care intervention

Stinging/allergic reactions to moisturisers (over the intervention period) · infants

Skin care intervention showed no clear difference in stinging/allergic reactions to moisturisers (over the intervention… compared with standard skin care or no skin care intervention (low certainty).

1 finding from 1 review