Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

251 questions · 277 findings · 23 reviews

No studies found 64 · 23.1%GRADE not reported 13 · 4.7%Very low 131 · 47.3%Low 59 · 21.3%Moderate 7 · 2.5%High 3 · 1.1%

Pharmacological interventions vs placebo

Smoking cessation · young people

It is very uncertain whether pharmacological interventions changes bupropion vs placebo Smoking cessation compared with placebo (very low certainty).

3 findings from 1 review

Pharmacological interventions vs placebo

Adverse events (control ‐ placebo) · young people
3 findings from 1 review

Movement interventions vs control

Activities of daily living · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

The review found no eligible studies for this question.

2 findings from 1 review

Movement interventions vs control

Neglect outcomes: effects persisting at least 1 month post intervention · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

The review found no eligible studies for this question.

1 finding from 1 review

Antidepressants vs placebo

Depression: meeting study criteria for depression at end of · people with stroke

It is very uncertain whether pharmacological interventions (antidepressants) changes depression: meeting study criteria for depression at end treatment… compared with placebo (very low certainty).

1 finding from 1 review

Antidepressants vs placebo

Adverse events: death ‐ at end of treatment (Analysis 1.14) · people with stroke

It is very uncertain whether pharmacological interventions (antidepressants) changes adverse events: death ‐ at end of treatment Analysis 1.12 compared with placebo (very low certainty).

1 finding from 1 review

Adverse effects of pharmacological intervention vs control

Breath holding · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide

It is very uncertain whether adverse effects of pharmacological intervention changes breath holding compared with control (very low certainty).

1 finding from 1 review

Adverse effects of pharmacological intervention vs control

Chest tightness · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide

It is very uncertain whether adverse effects of pharmacological intervention changes chest tightness compared with control (very low certainty).

1 finding from 1 review

Adverse effects of pharmacological intervention vs control

Cough · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide

Adverse effects of pharmacological intervention may leads to higher cough compared with control (low certainty).

1 finding from 1 review

Adverse effects of pharmacological intervention vs control

Adverse effects: pain on injection (solution deposition), Heft-Parker VAS 0-170 mm · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide

Adverse effects of pharmacological intervention showed no clear difference in pain on injection compared with control (low certainty).

1 finding from 1 review

Body awareness interventions vs control

Activities of daily living · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

It is very uncertain whether body awareness interventions changes activities of daily living: effects persisting at least 1 month post… compared with any control (very low certainty).

2 findings from 1 review

Body awareness interventions vs control

Neglect outcomes: effects persisting at least 1 month post intervention · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

It is very uncertain whether body awareness interventions changes neglect outcomes: effects persisting at least 1 month post… compared with any control (very low certainty).

1 finding from 1 review

Mental function interventions vs control

Activities of daily living · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

The review found no eligible studies for this question.

2 findings from 1 review

Mental function interventions vs control

Neglect outcomes: effects persisting at least 1 month post intervention · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

The review found no eligible studies for this question.

1 finding from 1 review