Question · asked by 1 review

Pharmacological interventions vs placebo: Smoking cessation

It is very uncertain whether pharmacological interventions changes bupropion vs placebo Smoking cessation compared with placebo (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Pharmacological interventions vs placebo
Bupropion vs placebo Smoking cessation · young people
It is very uncertain whether pharmacological interventions changes bupropion vs placebo Smoking cessation compared with placebo (very low certainty).
Tobacco cessation interventions for young people (2017) · Cochrane Headline outcomes only
RR 1.49 [0.55, 4.02]1 study · 207 participantsVery low
Pharmacological interventions vs placebo
Nicotine patch + bupropion vs nicotine patch + placebo Smoking cessation · young people
It is very uncertain whether pharmacological interventions changes nicotine patch + bupropion vs nicotine patch + placebo Smoking… compared with placebo (very low certainty).
Tobacco cessation interventions for young people (2017) · Cochrane Headline outcomes only
RR 1.05 [0.41, 2.69]1 study · 211 participantsVery low
Pharmacological interventions vs placebo
NRT vs placebo Smoking cessation · young people
It is very uncertain whether pharmacological interventions changes NRT vs placebo Smoking cessation compared with placebo (very low certainty).
Tobacco cessation interventions for young people (2017) · Cochrane Headline outcomes only
RR 1.11 [0.48, 2.58]2 studies · 385 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Tobacco cessation interventions for young people
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.