Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

178 questions · 190 findings · 36 reviews

No studies found 44 · 23.2%GRADE not reported 38 · 20%Very low 44 · 23.2%Low 43 · 22.6%Moderate 19 · 10%High 2 · 1.1%

Combined interventions vs usual care

Proportion of participants at work in the extended long term (≥ 5 years) · patients with coronary heart disease

It is very uncertain whether combined interventions changes proportion of participants at work in the extended long term (≥ 5… compared with usual care (very low certainty).

1 finding from 1 review

BRIEF FAMILY INTERVENTION vs usual care

Hospital admissions · patients with schizophrenia

It is very uncertain whether BRIEF FAMILY INTERVENTION changes service utilisation ‐ hospital admission ‐ medium to long term… compared with STANDARD CARE (very low certainty).

1 finding from 1 review

BRIEF FAMILY INTERVENTION vs usual care

Global state: relapse ‐ medium term ‐ not measured · patients with schizophrenia

BRIEF FAMILY INTERVENTION showed no clear difference in global state ‐ relapse ‐ medium to long term relapse rates (clinical… compared with STANDARD CARE (low certainty).

1 finding from 1 review

Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes

Catheter‐related blood stream infection · patients with a central venous catheter

Longer intervals (5‐15 days) (intervention) showed no clear difference in catheter‐related blood stream infection (CRBSI) compared with shorter intervals (2‐5 days) (control) between dressing changes (low certainty).

1 finding from 1 review

Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes

All‐cause mortality · patients with a central venous catheter

Longer intervals (5‐15 days) (intervention) showed no clear difference in all‐cause mortality compared with shorter intervals (2‐5 days) (control) between dressing changes (low certainty).

1 finding from 1 review

Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes

Pain № of participants: 193 (2 RCTs) · patients with a central venous catheter

Longer intervals (5‐15 days) (intervention) showed no clear difference in pain № of participants: 193 (2 RCTs) compared with shorter intervals (2‐5 days) (control) between dressing changes (low certainty).

1 finding from 1 review