Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,024 questions · 3,338 findings · 330 reviews

No studies found 735 · 22%GRADE not reported 282 · 8.4%Very low 962 · 28.8%Low 870 · 26.1%Moderate 384 · 11.5%High 105 · 3.1%

Lay health worker‐led psychological interventions vs usual care

Functional impairment ‐ not measured · adults with common mental disorders

Lay health worker‐led psychological interventions showed no clear difference in functional impairment/disability ‐ intermediate term (1 to 6 months… compared with usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Service utilisation · adults with common mental disorders

It is very uncertain whether lay health worker‐led psychological interventions changes service utilisation (1 to 6 months post intervention) compared with usual care (very low certainty).

1 finding from 1 review

Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs control intervention

Drug or alcohol use, or both following treatment completion ‐ Group‐based intervention As assessed by the ASI, TLFB or CIDI. High scores indicate greater symptom severity · Individuals with post‐traumatic stress disorder and comorbid substance use disorder
1 finding from 1 review

Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs control intervention

Treatment completers ‐ Individual‐based intervention · Individuals with post‐traumatic stress disorder and comorbid substance use disorder

The review found no eligible studies for this question.

1 finding from 1 review

Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs control intervention

Treatment completers ‐ Group‐based intervention · Individuals with post‐traumatic stress disorder and comorbid substance use disorder

Non‐trauma‐focused psychological intervention for PTSD and SUD or… showed no clear difference in treatment completers ‐ Group‐based intervention compared with control intervention (low certainty).

1 finding from 1 review

Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs control intervention

Severity of PTSD symptoms · Individuals with post‐traumatic stress disorder and comorbid substance use disorder
2 findings from 1 review

Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs control intervention

Drug or alcohol use, or both following treatment completion ‐ Individual‐based intervention · Individuals with post‐traumatic stress disorder and comorbid substance use disorder

The review found no eligible studies for this question.

1 finding from 1 review

Parenting interventions vs inactive control (usual care care, attention control, waitlist)

Substance use ‐ post‐intervention ‐ not reported · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood

The review found no eligible studies for this question.

1 finding from 1 review

Parenting interventions vs inactive control (usual care care, attention control, waitlist)

Parent relationship quality ‐ not reported · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood

The review found no eligible studies for this question.

1 finding from 1 review

Parenting interventions vs inactive control (usual care care, attention control, waitlist)

Parental self‐harm ‐ post‐intervention ‐ not reported · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood

The review found no eligible studies for this question.

1 finding from 1 review

Early intervention (mobilization or active exercise) vs usual care

Adverse events Proportion of participants with one or more events, or proportion of intervention sessions where an event occurred (falls, accidental dislodgement of attachments, haemodynamic instability, oxygen desaturation or any other adverse ev... · critically ill, mechanically ventilated adults
1 finding from 1 review