Cochrane · systematic review · CD010754
Early intervention (mobilization or active exercise) for critically ill adults in the intensive care unit
Doiron, KA, Hoffmann, TC, Beller, EM · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
Emergency and Critical CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
9
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 9 · 100%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Early intervention (mobilization or active exercise) versus usual care for critically ill adults
Population: critically ill, mechanically ventilated adults
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Physical function ‐ return to independent functional status at hospital discharge Defined as ability to perform 6 ADLs (bathing, dressing, eating, grooming, transferring from bed to chair, using the toilet) and walk independently, Early intervention (mobilization or active exercise) vs usual care | RR 1.71 [1.11, 2.64] | 1 study · 104 participants | Low Downgraded: risk of bias, imprecision |
Physical function ‐ independent ADLs total at ICU discharge Functional Independence Measure (0 ‐ 6) Early intervention (mobilization or active exercise) vs usual care | no estimate extracted | 1 study · 104 participants | Low Downgraded: risk of bias, imprecision |
Physical function ‐ Independent ADL total at hospital discharge Functional Independence Measure (0 ‐ 6) Early intervention (mobilization or active exercise) vs usual care | no estimate extracted | 1 study · 104 participants | Low Downgraded: risk of bias, imprecision |
Physical function Barthel score (0 ‐ 100) Early intervention (mobilization or active exercise) vs usual care | no estimate extracted | 1 study · 104 participants | Low Downgraded: risk of bias, imprecision |
Physical performance Acute Care Index of Function score at ICU discharge (0 ‐ 100) Early intervention (mobilization or active exercise) vs usual care | no estimate extracted | 1 study · 42 participants | Low Downgraded: risk of bias, imprecision |
Physical performance Physical Function ICU Test score at ICU discharge Early intervention (mobilization or active exercise) vs usual care | no estimate extracted | 1 study · 42 participants | Low Downgraded: risk of bias, imprecision |
Physical performance Short Physical Performance Battery score at ICU discharge Early intervention (mobilization or active exercise) vs usual care | no estimate extracted | 1 study · 184 participants | Low Downgraded: risk of bias, imprecision |
Physical performance Short Physical Performance Battery score at hospital discharge Early intervention (mobilization or active exercise) vs usual care | no estimate extracted | 1 study · 204 participants | Low Downgraded: risk of bias, imprecision |
Adverse events Proportion of participants with one or more events, or proportion of intervention sessions where an event occurred (falls, accidental dislodgement of attachments, haemodynamic instability, oxygen desaturation or any other adverse ev... Early intervention (mobilization or active exercise) vs usual care | no estimate extracted | 4 studies · 690 participants | Low Downgraded: imprecision |