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Evidence found and GRADE certainty

3,024 questions · 3,338 findings · 330 reviews

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No studies found 735 · 22%GRADE not reported 282 · 8.4%Very low 962 · 28.8%Low 870 · 26.1%Moderate 384 · 11.5%High 105 · 3.1%

Any Psychosocial intervention plus pharm vs pharm standard

Number of participants still in treatment at the end of · patients with treatment of opioid dependence

Any Psychosocial intervention plus pharm showed no clear difference in number of participants still in treatment at the end of compared with pharm standard (high certainty).

1 finding from 1 review

Any Psychosocial intervention plus pharm vs pharm standard

Abstinence · patients with treatment of opioid dependence

Any Psychosocial intervention plus pharm showed no clear difference in number of participants abstinent at the end of compared with pharm standard (high certainty).

1 finding from 1 review

Any of the interventions (CR, SE, SW, sealing with sealant materials, Hall Technique, or NRCC) vs Each other, placebo, or no treatment

Adverse events (any type) and safety of sealant · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

The review found no eligible studies for this question.

1 finding from 1 review

Any of the interventions (CR, SE, SW, sealing with sealant materials, Hall Technique, or NRCC) vs Each other, placebo, or no treatment

Subjective evaluation of the treatments by participants · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

The review found no eligible studies for this question.

1 finding from 1 review

Community health educational interventions vs control

Neonatal mortality · developing countries

Community health educational interventions may leads to lower neonatal mortality compared with control (low certainty).

2 findings from 1 review

Community health educational interventions vs control

Early neonatal mortality · developing countries

It is very uncertain whether community health educational interventions changes early neonatal mortality compared with control (very low certainty).

2 findings from 1 review

Community health educational interventions vs control

Late neonatal mortality · developing countries

It is very uncertain whether community health educational interventions changes late neonatal mortality compared with control (very low certainty).

2 findings from 1 review

Community health educational interventions vs control

Perinatal mortality · developing countries

Community health educational interventions probably leads to lower perinatal mortality compared with control (moderate certainty).

2 findings from 1 review

Lay health worker‐led interventions for adult patients with harmful or hazardous alcohol or substance use vs enhanced usual care

Quality of life · adult patients with harmful or hazardous alcohol or substance use

The review found no eligible studies for this question.

1 finding from 1 review

Lay health worker‐led interventions for adult patients with harmful or hazardous alcohol or substance use vs enhanced usual care

Adverse events ‐ death in past 12 months (RR > 1 denotes higher risk of death) · adult patients with harmful or hazardous alcohol or substance use

It is very uncertain whether lay health worker‐led interventions for adult patients with harmful… changes adverse events ‐ deaths (RR < 1 denotes lower risk) compared with enhanced usual care (very low certainty).

1 finding from 1 review

Interventions for involving older patients with multi‐morbidity in decision‐making about their health care vs usual care

Health status (a) Patient‐reported high self‐rated health at 6 months after baseline CDC Healthy Days Measure (CDC 2000): dichotomised as low (1 to 3) and high (4 to 5) · older patients with multi‐morbidity

It is very uncertain whether interventions for involving older patients with multi‐morbidity in… changes health status (a) Patient‐reported high self‐rated health at 6… compared with usual care (very low certainty).

1 finding from 1 review