Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

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579 questions · 601 findings · 56 reviews

No studies found 143 · 23.8%GRADE not reported 69 · 11.5%Very low 101 · 16.8%Low 142 · 23.6%Moderate 116 · 19.3%High 30 · 5%

Continuous negative extrathoracic pressure ventilation vs control

Intermittent positive pressure ventilation during hospital stay · children with acute hypoxaemic respiratory failure

It is very uncertain whether continuous negative extrathoracic pressure ventilation changes intermittent positive pressure ventilation during hospital stay compared with control (very low certainty).

1 finding from 1 review

Continuous vs intermittent bolus (nasogastric and orogastric tube) milk feeding ‐ all preterm infants less than 1500 grams

Necrotising enterocolitis · preterm infants less than 1500 grams

Continuous showed no clear difference in necrotising enterocolitis (NEC) compared with intermittent bolus (nasogastric and orogastric tube) milk feeding ‐… (low certainty).

1 finding from 1 review

Bilateral lateral rectus recession vs lateral rectus recession and medial rectus resection

Motor alignment at near Change in exotropia control at near fixation, measured from baseline to 3 years using the prism and alternate cover test · people with intermittent exotropia, aged 3 to < 11 years

Bilateral lateral rectus recession showed no clear difference in motor alignment at near Change in exotropia control at near… compared with unilateral lateral rectus recession with medial rectus resection (moderate certainty).

1 finding from 1 review

Patching vs active observation

Stereoacuity at distance Loss of ≥ 2 octaves near stereoacuity Measured using the Preschool Randot test 3 years after surgery · people with intermittent exotropia, aged less than 11 years

The review found no eligible studies for this question.

1 finding from 1 review

Patching vs active observation

Motor alignment at distance fixation Measured using PACT at 6 months · people with intermittent exotropia, aged less than 11 years

Patching showed no clear difference in motor alignment at distance fixation Measured using PACT at 6 months compared with active observation (high certainty).

1 finding from 1 review