Cochrane · systematic review · CD001819
Continuous nasogastric milk feeding versus intermittent bolus milk feeding for preterm infants less than 1500 grams
Sadrudin Premji, S, Chessell, L, Stewart, F · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 28.6%Low 5 · 71.4%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Continuous compared to intermittent bolus (nasogastric and orogastric tube) milk feeding ‐ all preterm infants less than 1500 grams
Population: preterm infants less than 1500 grams
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Age at full enteral feedings (days) Continuous vs intermittent bolus (nasogastric and orogastric tube) milk feeding ‐ all preterm infants less than 1500 grams | no estimate extracted | 7 studies · 628 participants | Low Downgraded: risk of bias, imprecision |
Feeding intolerance: number of days of feeding interruptions Continuous vs intermittent bolus (nasogastric and orogastric tube) milk feeding ‐ all preterm infants less than 1500 grams | no estimate extracted | 1 study · 171 participants | Very low Downgraded: risk of bias, imprecision |
Days to regain birth weight Continuous vs intermittent bolus (nasogastric and orogastric tube) milk feeding ‐ all preterm infants less than 1500 grams | no estimate extracted | 6 studies · 610 participants | Low Downgraded: risk of bias, imprecision |
End of intervention: rate of gain in weight Continuous vs intermittent bolus (nasogastric and orogastric tube) milk feeding ‐ all preterm infants less than 1500 grams | no estimate extracted | 5 studies · 433 participants | Very low Downgraded: risk of bias, imprecision |
End of intervention: rate of gain in length (cm/week) Continuous vs intermittent bolus (nasogastric and orogastric tube) milk feeding ‐ all preterm infants less than 1500 grams | no estimate extracted | 5 studies · 433 participants | Low Downgraded: risk of bias, imprecision |
End of intervention: rate of gain in head circumference (cm/week) Continuous vs intermittent bolus (nasogastric and orogastric tube) milk feeding ‐ all preterm infants less than 1500 grams | no estimate extracted | 5 studies · 433 participants | Low Downgraded: risk of bias, imprecision |
Necrotising enterocolitis (NEC) Continuous vs intermittent bolus (nasogastric and orogastric tube) milk feeding ‐ all preterm infants less than 1500 grams | RR 1.19 [0.67, 2.11] | 4 studies · 372 participants | Low Downgraded: risk of bias, imprecision |