Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

901 questions · 1,073 findings · 138 reviews

No studies found 166 · 15.5%GRADE not reported 310 · 28.9%Very low 213 · 19.9%Low 227 · 21.2%Moderate 132 · 12.3%High 25 · 2.3%

Higher BP target (< 150‐160/95‐105 mmHg) vs lower BP target (< 140/90 mmHg)

Serious adverse events: cardiovascular events · older adults with primary hypertension

Higher BP target (< 150‐160/95‐105 mmHg) showed no clear difference in cardiovascular serious adverse events compared with lower BP target (< 140/90 mmHg) (low certainty).

1 finding from 1 review

High‐intensity brief text messaging (SMS) vs low‐intensity brief text messaging

Documenting of matched pregnancy outcome data · Community health care workers, known as Health Surveillance Assistants (HSAs) (n = 156) associated with 30 health facilities.

High‐intensity brief text messaging (SMS) showed no clear difference in documenting of matched pregnancy outcome data compared with low‐intensity brief text messaging (low certainty).

1 finding from 1 review

High‐intensity brief text messaging (SMS) vs low‐intensity brief text messaging

Functioning of the RHIS · Community health care workers, known as Health Surveillance Assistants (HSAs) (n = 156) associated with 30 health facilities.

The review found no eligible studies for this question.

1 finding from 1 review

High‐intensity brief text messaging (SMS) vs low‐intensity brief text messaging

Health provider outcomes · Community health care workers, known as Health Surveillance Assistants (HSAs) (n = 156) associated with 30 health facilities.

The review found no eligible studies for this question.

1 finding from 1 review

ART sealant using high-viscosity glass ionomer (press-finger technique) vs No comparator

Caries-free sealed pits and fissures · Permanent teeth with sealed pits and fissures

The pooled caries-free rate was 85% at 6 years.

6 findings from 1 review
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ART sealant using high-viscosity glass ionomer (press-finger technique) vs No comparator

Retention of sealant (complete or partial retention) · Permanent teeth

The pooled retention rate was 75% at 1 year.

5 findings from 1 review
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Vitamin D (higher dose) + micronutrient(s) vs vitamin D (lower dose) + micronutrient(s)

Adverse effect: hypercalciuria As defined by trialists Time frame: 3 months · children under 5 years of age

Vitamin D (higher dose) + micronutrient(s) showed no clear difference in adverse effect: hypercalciuria As defined by trialists Time frame: 3… compared with vitamin D (lower dose) + micronutrient(s) (low certainty).

1 finding from 1 review

Vitamin D (higher dose) + micronutrient(s) vs vitamin D (lower dose) + micronutrient(s)

Hypercalcaemia · children under 5 years of age

Vitamin D (higher dose) + micronutrient(s) showed no clear difference in adverse effect: hypercalcaemia As defined by trialists Time frame:… compared with vitamin D (lower dose) + micronutrient(s) (moderate certainty).

1 finding from 1 review

Summary of findings: Higher bladder volume vs lower bladder volume

Acute and late GI toxicity (grade 2+) · Men undergoing RT for prostate cancer

Summary of findings: Higher bladder volume showed no clear difference in acute and late GI toxicity (grade 2+) compared with lower bladder volume (low certainty).

1 finding from 1 review