Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

236 questions · 253 findings · 35 reviews · Headline outcomes only

No studies found 47 · 18.6%GRADE not reported 7 · 2.8%Very low 63 · 24.9%Low 76 · 30%Moderate 40 · 15.8%High 20 · 7.9%

Any anti‐adhesion therapy vs anti‐adhesion therapy B following operative hysteroscopy

Presence of intrauterine adhesions at second‐look hysteroscopy (6‐12 weeks) · women treated by operative hysteroscopy for uterine pathology

Any anti‐adhesion therapy A may leads to lower presence of intrauterine adhesions at second‐look hysteroscopy (6‐12… compared with anti‐adhesion therapy B following operative hysteroscopy (low certainty).

1 finding from 1 review

Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone

Need for additional anaesthesia during surgery Assessed dichotomously, as 'additional anaesthesia given' or 'additional anaesthesia not given' · adults undergoing phacoemulsification cataract surgery

Topical anaesthesia plus intracameral lidocaine showed no clear difference in need for additional anaesthesia during surgery Assessed… compared with topical anaesthesia alone (low certainty).

1 finding from 1 review

Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone

Intraoperative adverse surgical events attributable to choice of anaesthesia · adults undergoing phacoemulsification cataract surgery

Topical anaesthesia plus intracameral lidocaine showed no clear difference in intraoperative adverse surgical events attributable to choice of… compared with topical anaesthesia alone (low certainty).

1 finding from 1 review

Any anti‐adhesion therapy vs placebo or no treatment following operative hysteroscopy

Presence of intrauterine adhesions at second‐look hysteroscopy (6‐12 weeks) · women treated by operative hysteroscopy for uterine pathology associated with subfertility or adverse pregnancy outcome

Any anti‐adhesion therapy may leads to lower presence of intrauterine adhesions at second‐look hysteroscopy… compared with placebo or no treatment following operative hysteroscopy (low certainty).

1 finding from 1 review