Cochrane · systematic review · CD001302
Volume expanders for the prevention of ovarian hyperstimulation syndrome
Youssef, MA, Mourad, S · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Gynaecology and FertilityAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
6
No studies
6
Included studies
NR
No studies 6 · 50%Ungraded 0 · 0%Very low 3 · 25%Low 2 · 16.7%Moderate 1 · 8.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Human albumin versus placebo or no treatment for the prevention of OHSS
Population: women at high risk of OHSS
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Moderate or severe OHSS Human albumin vs placebo or no treatment | OR 0.67 [0.47, 0.95] | 7 studies · 1452 participants | Very low Downgraded: risk of bias |
Live birth Human albumin vs placebo or no treatment | no estimate extracted | NR | No studies |
Pregnancy rate Human albumin vs placebo or no treatment | OR 0.72 [0.55, 0.94] | 7 studies · 1069 participants | Moderate Downgraded: risk of bias |
Adverse effects Human albumin vs placebo or no treatment | no estimate extracted | NR | No studies |
HES versus placebo or no treatment for the prevention of OHSS
Population: Women at high risk of OHSS
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Moderate or severe OHSS HES vs placebo or no treatment | OR 0.27 [0.12, 0.59] | 2 studies · 272 participants | Very low Downgraded: risk of bias |
Live birth HES vs placebo or no treatment | no estimate extracted | NR | No studies |
Pregnancy rate HES vs placebo or no treatment | OR 1.2 [0.49, 2.93] | 1 study · 168 participants | Very low Downgraded: risk of bias |
Adverse effects HES vs placebo or no treatment | no estimate extracted | NR | No studies |
Mannitol versus placebo / no treatment for the prevention of OHSS
Population: women at high risk of OHSS
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Moderate or severe OHSS Mannitol vs placebo / no treatment | OR 0.38 [0.22, 0.64] | 1 study · 226 participants | Low Downgraded: risk of bias, imprecision |
Live birth Mannitol vs placebo / no treatment | no estimate extracted | NR | No studies |
Pregnancy rate Mannitol vs placebo / no treatment | OR 0.85 [0.47, 1.55] | 1 study · 226 participants | Low Downgraded: risk of bias, imprecision |
Adverse effects Mannitol vs placebo / no treatment | no estimate extracted | NR | No studies |