Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review
Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less
Fluoride mouthrinse combined with fluoride toothpaste showed no clear difference in unacceptability of treatment (drop-outs / leaving study early) compared with fluoride mouthrinse alone; GRADE not reported.
1 finding from 1 review
Incidence of initial caries around brackets, aesthetic-zone teeth only · Orthodontic patients (any age) undergoing orthodontic treatment (mostly fixed appliances)
When only aesthetic-zone teeth (incisors and canines) were considered, two studies reported a significant reduction in initial caries incidence favoring fluoride mouthrinse (ungraded, narrative; no pooled estimate).
1 finding from 1 review
Incidence of proximal (interdental) caries lesions from bitewing radiographs · Orthodontic patients (any age) undergoing orthodontic treatment (mostly fixed appliances)
Only one included study assessed proximal caries incidence from bitewing radiographs; it was not included in the meta-analysis and no pooled estimate is available (ungraded).
1 finding from 1 review
Incidence of initial enamel caries / white spot lesions adjacent to bracket base (subject level, dichotomized) · Orthodontic patients (any age) undergoing orthodontic treatment (mostly fixed appliances)
Adding a fluoride mouthrinse to daily fluoride toothpaste produced a small reduction in the incidence of initial caries/white spot lesions adjacent to brackets (pooled risk difference -0.07, 95% CI -0.14 to -0.01; 5 studies, 491 subjects), but the authors judged the overall evidence inconclusive (ungraded).
1 finding from 1 review
Side effects or other adverse events · Orthodontic patients (any age) undergoing orthodontic treatment (mostly fixed appliances)
No adverse effects were reported in any of the seven included studies (ungraded).
1 finding from 1 review
Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less
Fluoride toothpaste showed no clear difference in unacceptability of treatment (drop-outs) compared with fluoride mouthrinse; GRADE not reported.
1 finding from 1 review
RR 0.89 [0.78, 1.00]
5 studies
GRADE not reported
Proportion of children developing new caries (permanent) · Children and adolescents aged 16 years or less
Fluoride toothpaste showed no clear difference in proportion of children developing new caries (permanent) compared with fluoride mouthrinse; GRADE not reported.
1 finding from 1 review
RR 0.90 [0.60, 1.37]
1 study
GRADE not reported
Caries increment in permanent teeth · Children and adolescents aged 16 years or less
1 finding from 1 review
Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less
Fluoride toothpaste showed no clear difference in unacceptability of treatment (drop-outs) compared with any other topical fluoride (gel or mouthrinse); GRADE not reported.
1 finding from 1 review
RR 0.88 [0.78, 1.00]
6 studies
GRADE not reported
Caries increment in permanent teeth · Children and adolescents aged 16 years or less
1 finding from 1 review
Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review
Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less
Fluoride mouthrinse combined with fluoride toothpaste showed no clear difference in unacceptability of treatment (drop-outs / leaving study early) compared with fluoride toothpaste alone; GRADE not reported.
1 finding from 1 review
Adverse effects (tooth staining and other side effects) · Children and adolescents aged 16 years or less
1 finding from 1 review
Adverse effects: dental fluorosis · Children and adolescents aged 16 years or less
The review found no eligible studies for this question.
1 finding from 1 review
Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less
Fluoride mouthrinse, gel or varnish combined with fluoride… showed no clear difference in unacceptability of treatment (drop-outs / leaving study early) compared with fluoride toothpaste alone; GRADE not reported.
1 finding from 1 review
Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review
Caries increment in permanent teeth · Children and adolescents aged 16 years or less
1 finding from 1 review
Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or younger (permanent dentition)
7 findings from 1 review
Show 4 more findings
PF 0.28 [0.19, 0.37]
22 studies
GRADE not reported
PF 0.40 [0.31, 0.49]
17 studies
GRADE not reported
PF 0.24 [0.21, 0.28]
70 studies
GRADE not reported
PF 0.46 [0.30, 0.63]
7 studies
GRADE not reported
Caries increment on primary (deciduous) tooth surfaces (d(e/m)fs), prevented fraction · Children with primary (deciduous) teeth (younger children)
5 findings from 1 review
PF 0.26 [-0.11, 0.63]
2 studies
GRADE not reported
PF 0.41 [0.26, 0.55]
2 studies
GRADE not reported
PF 0.27 [0.08, 0.48]
3 studies
GRADE not reported
Show 2 more findings
PF 0.33 [0.22, 0.44]
5 studies
GRADE not reported
PF 0.33 [0.19, 0.48]
3 studies
GRADE not reported