Question · asked by 1 review
Fluoride mouthrinse, gel or varnish combined with fluoride toothpaste (any combined regimen) vs Fluoride toothpaste alone: Adverse effects (tooth staining and other side effects)
- Population
- Children and adolescents aged 16 years or less
- Intervention
- Fluoride mouthrinse, gel or varnish combined with fluoride toothpaste (any combined regimen)
- Comparison
- Fluoride toothpaste alone
- Outcome
- Adverse effects (tooth staining and other side effects)
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Fluoride mouthrinse, gel or varnish combined with fluoride toothpaste (any combined regimen) vs Fluoride toothpaste alone Adverse effects (tooth staining and other side effects) · Children or adolescents aged 16 years or less Combinations of topical fluoride (toothpastes, mouthrinses, gels, varnishes) versus single topical fluoride… (2004) · Cochrane All outcomes | Adverse-effect data scarcely reported: a stain score in one trial and 'any side effects' in one trial without complete or useable data (stated 'no side effects observed in both groups'). No useful information on tooth… | Not reported | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Combinations of topical fluoride (toothpastes, mouthrinses, gels, varnishes) versus single topical fluoride for preventing dental caries… 2004 · Cochrane All outcomes | 2001-10 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.