Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

18 questions · 18 findings · 7 reviews

No studies found 8 · 44.4%GRADE not reported 1 · 5.6%Very low 1 · 5.6%Low 4 · 22.2%Moderate 2 · 11.1%High 2 · 11.1%

Summary of findings table ‐ Adjunctive therapies in addition to land‐based exercise therapy vs land‐based exercise therapy

Adverse events · Patients with osteoarthritis of the knee or hip

Summary of findings table ‐ Adjunctive therapies in addition to… showed no clear difference in adverse events compared with land‐based exercise therapy (low certainty).

1 finding from 1 review

Combination of manual therapy and exercise following joint distension vs sham ultrasound following joint distension

Adverse events · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy and exercise following joint distension leads to lower adverse events compared with sham ultrasound following joint distension (high certainty).

1 finding from 1 review

Summary of findings table ‐ Adjunctive therapies in addition to land‐based exercise therapy vs placebo adjunctive therapies

Adverse events · Patients with osteoarthritis of the knee or hip

Summary of findings table ‐ Adjunctive therapies in addition to… showed no clear difference in adverse events compared with placebo adjunctive therapies (low certainty).

1 finding from 1 review

Combination of manual therapy, exercise, electrotherapy and oral NSAID vs oral NSAID

Adverse events Pain persisting longer than 2 hours after treatment (during the 3‐week treatment period) · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy, exercise, electrotherapy and oral NSAID may leads to higher adverse events Pain persisting longer than 2 hours after treatment… compared with oral NSAID (low certainty).

1 finding from 1 review