Change in height-for-age z score · Children aged ≤6 years (early childhood)
The association between baseline caries and declining height-for-age persisted after adjustment (coefficient -0.02); ungraded.
1 finding from 1 review
Stunting · Children aged ≤6 years (early childhood)
One Nepalese cross-sectional study found caries severity significantly correlated with chronic malnutrition/stunting (HAZ; p<0.0001), especially in rural children; ungraded, no effect size reported.
3 findings from 1 review
Risk of malnutrition (younger children, 6 months to 6 years) · Children aged ≤6 years (early childhood)
One Nepalese cross-sectional study found no significant association between severe ECC and malnutrition risk in children under 6 (mean difference 0.13, p=0.609); ungraded.
1 finding from 1 review
Relative abundance of Veillonella spp. · Young children with early childhood caries and caries-free controls
Veillonella spp. mean relative abundance was higher in ECC children, without a comparative effect estimate or CI.
Mean relative abundance (%) ECC 3.29 (SD 6.83) vs caries-free 2.13 (SD 2.30)
1 study · 87 participants
GRADE not reported
Meta-Analysis Using NGS Data: The Veillonella Species in Dental Caries. 2022 All outcomesSaliva and supragingival biofilm (pooled) · Overall (all sample types)
MD 2.22 [0.54, 3.90]
6 studies · 319 participants
Very low
MD -1.05 [-7.67, 5.57]
2 studies · 161 participants
GRADE not reported
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Number of detected salivary bacterial genera · Young children with early childhood caries and caries-free controls
Fewer salivary bacterial genera were reported in the caries-affected group, without a comparative effect estimate or CI.
1 finding from 1 review
Relative abundance of dominant salivary microbial community (7 genera) · Young children with early childhood caries and caries-free controls
The reported multi-genus community had similar relative abundance in caries-affected and caries-free children, without a comparative effect estimate or CI.
1 finding from 1 review
Streptococcus mutans and Veillonella spp. levels · Young children with early childhood caries and caries-free controls
Veillonella spp. levels were reported as substantially greater in caries subjects, but the review gave no numerical effect estimate or CI.
1 finding from 1 review
Correlation of Veillonella spp. with acidogenic streptococci · Young children with early childhood caries and caries-free controls
Veillonella spp. levels were correlated with acidogenic streptococci in white spot lesions (r²=0.38); no CI was reported.
1 finding from 1 review
Relative abundance of Veillonella spp. · Children under 6 years with severe early childhood caries and caries-free controls
Veillonella spp. mean relative abundance was lower in the S-ECC group; no comparative effect estimate or CI was reported.
1 finding from 1 review
Relative abundance of S. mutans in saliva · Children under 6 years with severe early childhood caries and caries-free controls
S. mutans median relative abundance was higher in the S-ECC group, without a comparative effect estimate or CI.
1 finding from 1 review
Streptococcus relative abundance · Children under 6 years with severe early childhood caries and caries-free controls
Streptococcus mean relative abundance was slightly higher in the S-ECC group; no comparative effect estimate or CI was reported.
1 finding from 1 review
Veillonella spp. and Streptococcus mutans interaction · Children under 6 years with severe early childhood caries and caries-free controls
The study reported a possible role for Veillonella spp. in supporting cariogenic species, without a quantitative effect estimate.
1 finding from 1 review
Veillonella spp. may promote proliferation or survival of cariogenic species, as shown for interactions between Veillonella spp. and S. mutans.
1 study · 82 participants
GRADE not reported
Veillonella dispar relative abundance · Children under 6 years with severe early childhood caries and caries-free controls
Veillonella dispar median relative abundance was higher in the S-ECC group, without a comparative effect estimate or CI.
1 finding from 1 review
Implant failure · Patients who are having osseointegrated root-form dental implants
Early loading showed no clear difference in implant failure compared with conventional loading; GRADE not reported.
1 finding from 1 review
RR 1.55 [0.46, 5.18]
2 studies
GRADE not reported
Marginal bone level change · Patients who are having osseointegrated root-form dental implants
Early loading showed no clear difference in marginal bone level changes compared with conventional loading; GRADE not reported.
1 finding from 1 review
MD -0.04 [-0.15, 0.07]
2 studies
GRADE not reported
Prosthesis failure · Patients who are having osseointegrated root-form dental implants
It is very uncertain whether early loading changes prosthesis failure compared with conventional loading (very low certainty).
1 finding from 1 review
Caries arrest · Children with dentine carious lesions (ICDAS 4-5) in primary teeth
Twice-yearly 38% SDF was reported to arrest more caries than once-yearly application (24-month rates 91% vs 79%; ungraded).
1 finding from 1 review
Incidence of incisal trauma · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase) with headgear showed no clear difference in incidence of incisal trauma compared with early treatment (two-phase) with functional appliance; GRADE not reported.
2 findings from 1 review
Final ANB · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase) with headgear showed no clear difference in final ANB compared with early treatment (two-phase) with functional appliance; GRADE not reported.
2 findings from 1 review
PAR score · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase) with headgear showed no clear difference in PAR score compared with early treatment (two-phase) with functional appliance; GRADE not reported.
1 finding from 1 review