Severe early childhood caries vs Caries-free controls: Relative abundance of S. mutans in saliva
S. mutans median relative abundance was higher in the S-ECC group, without a comparative effect estimate or CI.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Severe early childhood caries vs Caries-free controls Streptococcus mutans relative abundance · Children under 6 years with severe early childhood caries and caries-free controls · USA S. mutans median relative abundance was higher in the S-ECC group, without a comparative effect estimate or CI. A systematic review of Streptococcus Mutans and Veillonellae species interactions in dental caries… (2025) All outcomes | Median relative abundance (%) caries 0.73 (range 0.02-22.9) vs control 0.15 (0.006-10.4) | 1 study · 50 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| A systematic review of Streptococcus Mutans and Veillonellae species interactions in dental caries progression: Positive or Negative impact? 2024 All outcomes | 18 July 2023 (databases searched from inception) | 7 | Not applicable |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.