Treatment failure; rehospitalization or adjustment of antimicrobial treatment (or both), only first episode in number of participants · children with cancer
Very early discharge showed no clear difference in treatment failure; rehospitalization or adjustment of antimicrobial… compared with early discharge (low certainty).
1 finding from 1 review
RR 0.32 [0.07, 1.4]
Studies not reported
Low
Adverse events: participants incurring one or more adverse events · participants undergoing rehabilitation following surgery for flexor tendon injuries of the handa
It is very uncertain whether early active flexion plus controlled passive exercise regimen changes adverse events: participants incurring one or more adverse events compared with early controlled passive exercise regimen (very low certainty).
1 finding from 1 review
Early angular outcome at 6 weeks for Tubiana grade I disease (total passive extension deficit (TPED) of the MCPJ, PIPJ and DIPJ for preoperative contractures with a TPED of 0 to 45 degrees) Early angular outcome at 6 weeks for Tubiana grade II dis... · 125 hands in 121 participants with Dupuytren's disease of the fingers for early outcomes (van Rijssen 2006)
1 finding from 1 review
Paraesthesia · 125 hands in 121 participants with Dupuytren's disease of the fingers for early outcomes (van Rijssen 2006)
1 finding from 1 review
Any breastfeeding at 6 weeks postpartum · healthy mothers and term infants
Early discharge showed no clear difference in women breastfeeding (exclusively or partially) at 6 weeks postpartum compared with standard discharge (moderate certainty).
1 finding from 1 review
Significant maternal morbidity one or more of the following: significant postpartum haemorrhage requiring blood transfusion; maternal admission to intensive care unit; uterine rupture; hysterectomy · pregnant women with a term suspected compromised baby
Planned early delivery showed no clear difference in significant maternal morbidity one or more of the following:… compared with expectant management (low certainty).
1 finding from 1 review
Umbilical artery pH · pregnant women (at term) requesting epidural analgesia in labour (regardless of whether the labour was spontaneous or induced)
1 finding from 1 review
Costs · small asymptomatic AAA
Early open repair showed no clear difference in costs (per participant) ( compared with ultrasound surveillance (moderate certainty).
1 finding from 1 review
Physical function · critically ill, mechanically ventilated adults
1 finding from 1 review
Adverse events Proportion of participants with one or more events, or proportion of intervention sessions where an event occurred (falls, accidental dislodgement of attachments, haemodynamic instability, oxygen desaturation or any other adverse ev... · critically ill, mechanically ventilated adults
1 finding from 1 review
Composite outcome – randomised trials Composite outcome of incidence (events divided by number of eligible participants admitted to the hospital during the study period) of cardiac arrests without a pre‐existing NFR order, unplanned ICU admissions... · adult on acute hospital wards at risk of clinical deterioration
1 finding from 1 review
AOR 0.98 [0.83, 1.16]
364094 participants
Moderate
Cognitive outcome · preterm infants
1 finding from 1 review
Motor outcome at preschool age (Griffiths Locomotor, McCarthy, MABC) · preterm infants
1 finding from 1 review
All‐cause mortality during hospital stay · preterm infants
Early treatment showed no clear difference in all‐cause mortality during hospital stay compared with expectant management (moderate certainty).
1 finding from 1 review
Proportion of infants requiring surgical PDA ligation or transcatheter occlusion · preterm infants
It is very uncertain whether early treatment changes proportion of infants requiring surgical PDA ligation or… compared with expectant management (very low certainty).
1 finding from 1 review
Proportion of infants receiving any pharmacotherapy for a hemodynamically significant PDA · preterm infants
Early treatment may leads to higher proportion of infants receiving any pharmacotherapy for a… compared with expectant management (low certainty).
1 finding from 1 review
Chronic lung disease · preterm infants
Early treatment showed no clear difference in chronic lung disease compared with expectant management (moderate certainty).
1 finding from 1 review
Severe intraventricular hemorrhage in infants who received neuroimaging · preterm infants
Early treatment showed no clear difference in severe Intraventricular hemorrhage (grades III and IV) compared with expectant management (low certainty).
1 finding from 1 review
NEC ≥ stage II · preterm infants
Early treatment showed no clear difference in necrotizing enterocolitis (NEC; stage 2 or greater) compared with expectant management (low certainty).
1 finding from 1 review
Chronic lung disease · preterm infants
Very early treatment showed no clear difference in chronic lung disease compared with expectant management (low certainty).
1 finding from 1 review