Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

129 questions · 141 findings · 13 reviews · Common Mental Disorders

No studies found 38 · 27%GRADE not reported 2 · 1.4%Very low 29 · 20.6%Low 39 · 27.7%Moderate 26 · 18.4%High 7 · 5%

New‐generation antidepressants vs placebo

Repetition of SH at post‐intervention · self‐harm in adults

It is very uncertain whether newer generation antidepressants (NGAs) changes repetition of SH by post‐intervention (NGA class)№ of participants:… compared with placebo (very low certainty).

3 findings from 1 review

Antidepressants vs placebo

Clinical response of depression · adults with psychotic depression

It is very uncertain whether antidepressant changes clinical response of depression compared with placebo (very low certainty).

1 finding from 1 review