Anticonvulsant showed no clear difference in alcohol Withdrawal Seizures post treatment ‐ Any Anticonvulsant vs.… compared with placebo (moderate certainty).
Anticonvulsant showed no clear difference in dropout ‐ Any Anticonvulsant vs. Placebo compared with placebo (moderate certainty).
Anticonvulsant showed no clear difference in alcohol withdrawal seizures ‐ Any Anticonvulsant vs any Other compared with other Drugs (low certainty).
Anticonvulsant showed no clear difference in adverse events ‐ Any Anticonvulsant vs any Other compared with other Drugs (moderate certainty).
Anticonvulsant showed no clear difference in dropout ‐ Any Anticonvulsant vs any Other compared with other Drugs (moderate certainty).
Anticonvulsant showed no clear difference in alcohol Withdrawal Seizures post treatment ‐ Phenytoin vs. Placebo compared with placebo (moderate certainty).
Anticonvulsant showed no clear difference in adverse events compared with placebo (moderate certainty).
Anticonvulsants showed no clear difference in dropouts compared with placebo (moderate certainty).
Anticonvulsants showed no clear difference in continuous abstinence compared with placebo (moderate certainty).
Anticonvulsants showed no clear difference in adverse events—withdrawn for medical reasons compared with placebo (moderate certainty).
Any anticonvulsant showed no clear difference in dropout Number of participants who did not complete the treatment compared with placebo (moderate certainty).
Any anticonvulsant showed no clear difference in use of cocaine (self reported or objective) Number of participants… compared with placebo (moderate certainty).
Any anticonvulsant may leads to higher side effect Number of participants reporting at least 1 side effect… compared with placebo (low certainty).
Comparison 2: anticonvulsants/GABAs probably leads to higher global Impressions scale change item (CGI‐I or similar): no. of… compared with placebo (moderate certainty).
It is very uncertain whether comparison 2: anticonvulsants/GABAs changes dropouts due to adverse events (acute phase) compared with placebo (very low certainty).