Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

594 questions · 624 findings · 70 reviews

No studies found 151 · 24.2%GRADE not reported 53 · 8.5%Very low 174 · 27.9%Low 129 · 20.7%Moderate 82 · 13.1%High 35 · 5.6%

Benefits and harms of CSF plus antibiotics vs antibiotics alone

Duration of grade IV neutropenia (lower values signify better outcomes) · people with chemotherapy‐induced febrile neutropenia

Benefits and harms of CSF plus antibiotics showed no clear difference in duration of grade IV neutropenia (lower values signify better… compared with antibiotics alone (low certainty).

1 finding from 1 review

Benefits and harms of CSF plus antibiotics vs antibiotics alone

Time to recovery from fever (lower values signify better outcomes) · people with chemotherapy‐induced febrile neutropenia

Benefits and harms of CSF plus antibiotics showed no clear difference in time to recovery from fever (lower values signify better outcomes) compared with antibiotics alone (low certainty).

1 finding from 1 review

Benefits and harms of CSF plus antibiotics vs antibiotics alone

Time to withdrawal from ATB (lower values signify better outcomes) · people with chemotherapy‐induced febrile neutropenia

Benefits and harms of CSF plus antibiotics showed no clear difference in time to withdrawal from ATB (lower values signify better outcomes) compared with antibiotics alone (low certainty).

1 finding from 1 review