Antibiotics vs placebo
Total adverse effects ‐ not reported · women having elective vaginal hysterectomy
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
594 questions · 624 findings · 70 reviews
No studies found 151 · 24.2%GRADE not reported 53 · 8.5%Very low 174 · 27.9%Low 129 · 20.7%Moderate 82 · 13.1%High 35 · 5.6%
Antibiotics vs placebo
Total postoperative infections ‐ early and late · women having elective abdominal hysterectomy
Antibiotics may leads to lower total postoperative infections ‐ early and late compared with placebo (low certainty).
1 finding from 1 review
- RR 0.38 [0.21, 0.67]1 study · 158 participantsLow
Antibiotics vs placebo
Abdominal surgical site infection · women having elective abdominal hysterectomy
Antibiotics probably leads to lower abdominal wound infection compared with placebo (moderate certainty).
1 finding from 1 review
- RR 0.51 [0.36, 0.73]11 studies · 2247 participantsModerate
Antibiotics vs placebo
Urinary tract infection · women having elective abdominal hysterectomy
Antibiotics probably leads to lower urinary tract infection compared with placebo (moderate certainty).
1 finding from 1 review
- RR 0.41 [0.31, 0.53]11 studies · 2705 participantsModerate
Antibiotics vs placebo or no treatment
Number of participants who were not cured at · children < 24 months with ongoing symptoms (cough/wheeze) post‐acute bronchiolitis
Antibiotics showed no clear difference in number of participants who were not cured at compared with placebo or no treatment (low certainty).
1 finding from 1 review
- Antibiotics for persistent cough or wheeze following acute bronchiolitis in children 2017 · Cochrane Headline outcomes onlyOR 0.69 [0.37, 1.28]2 studies · 249 participantsLow
Antibiotics vs placebo or no treatment
Number of participants rehospitalised for a respiratory illness · children < 24 months with ongoing symptoms (cough/wheeze) post‐acute bronchiolitis
Antibiotics showed no clear difference in number of participants rehospitalised for a respiratory illness compared with placebo or no treatment (low certainty).
1 finding from 1 review
- Antibiotics for persistent cough or wheeze following acute bronchiolitis in children 2017 · Cochrane Headline outcomes onlyOR 1.19 [0.67, 2.12]2 studies · 240 participantsLow
Antibiotics vs placebo or no treatment
Proportion of participants with recurrent wheeze · children < 24 months with ongoing symptoms (cough/wheeze) post‐acute bronchiolitis
Antibiotics showed no clear difference in proportion of participants with recurrent wheeze compared with placebo or no treatment (low certainty).
1 finding from 1 review
- Antibiotics for persistent cough or wheeze following acute bronchiolitis in children 2017 · Cochrane Headline outcomes onlyOR 0.47 [0.06, 3.95]2 studies · 240 participantsLow
Antibiotics vs placebo, no treatment or therapy of unproven effectiveness
Complete resolution of OME at 2 to 3 months · Children with otitis media with effusion
Antibiotics probably leads to higher complete resolution of OME at 2 to 3 months compared with placebo, no treatment or therapy of unproven effectiveness (moderate certainty).
2 findings from 1 review
- RR 2 [1.58, 2.53]6 studies · 484 participantsModerate
- RR 1.98 [1.47, 2.67]14 studies · 2091 participantsLow
Antibiotics vs placebo, no treatment or therapy of unproven effectiveness
Adverse effects · Children with otitis media with effusion
Antibiotics may leads to higher adverse effects compared with placebo, no treatment or therapy of unproven effectiveness (low certainty).
1 finding from 1 review
- RR 2.15 [1.29, 3.6]5 studies · 742 participantsLow
Antibiotics vs placebo, no treatment or therapy of unproven effectiveness
Complete resolution of OME at more than 6 months · Children with otitis media with effusion
Antibiotics may leads to higher complete resolution of OME at more than 6 months compared with placebo, no treatment or therapy of unproven effectiveness (low certainty).
1 finding from 1 review
- RR 1.75 [1.41, 2.18]5 studies · 606 participantsLow
Antibiotics vs placebo, no treatment or therapy of unproven effectiveness
Insertion of ventilation tubes · Children with otitis media with effusion
Antibiotics showed no clear difference in insertion of ventilation tubes compared with placebo, no treatment or therapy of unproven effectiveness (low certainty).
1 finding from 1 review
- RR 0.9 [0.46, 1.78]2 studies · 121 participantsLow
Antibiotics vs placebo, no treatment or therapy of unproven effectiveness
Tympanic membrane sequelae · Children with otitis media with effusion
Antibiotics showed no clear difference in tympanic membrane sequelae compared with placebo, no treatment or therapy of unproven effectiveness (low certainty).
1 finding from 1 review
- RR 0.42 [0.18, 1.01]1 study · 103 participantsLow
Antibiotics vs placebo
Clinical failure rate · patients with uncomplicated acute maxillary sinusitis
Antibiotics probably leads to lower clinical failure rate compared with placebo (moderate certainty).
2 findings from 1 review
- RR 0.66 [0.47, 0.94]5 studies · 1084 participantsModerate
- RR 0.85 [0.36, 1.98]1 study · 169 participantsLow
Antibiotics vs placebo
Quality of life and activity impairment · patients with uncomplicated acute maxillary sinusitis
1 finding from 1 review
- no estimate extractedStudies not reportedVery low
Antibiotics vs no treatment during postpartum period
Postpartum endometritis · women with management of intra‐amniotic infection
It is very uncertain whether antibiotics changes postpartum endometritis compared with no treatment during postpartum period (very low certainty).
1 finding from 1 review
- Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes onlyRR 1.48 [0.68, 3.24]1 study · 116 participantsVery low
Antibiotics vs no treatment during postpartum period
Duration of maternal and neonatal hospital stay · women with management of intra‐amniotic infection
1 finding from 1 review
- Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes onlyno estimate extracted0 studies · 0 participantsGRADE not reported
Antibiotics vs no treatment during postpartum period
Postpartum readmission for endometritis · women with management of intra‐amniotic infection
1 finding from 1 review
- Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes onlyno estimate extracted0 studies · 0 participantsGRADE not reported
Antibiotics vs no treatment during postpartum period
Failure of treatment · women with management of intra‐amniotic infection
1 finding from 1 review
- Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes onlyno estimate extracted0 studies · 0 participantsGRADE not reported
Antibiotics vs placebo during postpartum period
Maternal and neonatal mortality · women with management of intra‐amniotic infection
1 finding from 1 review
- Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes onlyno estimate extracted0 studies · 0 participantsGRADE not reported
Antibiotics vs placebo during postpartum period
Maternal and neonatal severe infection · women with management of intra‐amniotic infection
1 finding from 1 review
- Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes onlyno estimate extracted0 studies · 0 participantsGRADE not reported