Antibiotics vs surgery
- Appendectomy versus antibiotic treatment for acute appendicitis 2024 · Cochrane Headline outcomes onlyno estimate extracted9 studies · 1396 participantsVery low
Antibiotic leads to lower surgical wound infection (SWI) compared with no antibiotic/placebo (high certainty).
It is very uncertain whether antibiotics changes mortality compared with surgery (very low certainty).
Antibiotics may leads to lower success of treatment compared with surgery (low certainty).
It is very uncertain whether antibiotics changes clostridium difficile diarrhoea compared with surgery (very low certainty).
It is very uncertain whether antibiotics changes intra‐abdominal abscess or collection compared with surgery (very low certainty).
It is very uncertain whether antibiotics changes reoperation compared with surgery (very low certainty).
It is very uncertain whether antibiotics changes length of hospital stay (days) compared with surgery (very low certainty).
It is very uncertain whether antibiotic prophylaxis changes all wound infections (SSSI + DSSI) compared with placebo (very low certainty).
Antibiotic prophylaxis showed no clear difference in DSSI compared with placebo (moderate certainty).
Antibiotic prophylaxis showed no clear difference in DSSI ‐ low infection risk environment compared with placebo (moderate certainty).
Antibiotic prophylaxis showed no clear difference in DSSI ‐ high infection risk environment compared with placebo (low certainty).
It is very uncertain whether antibiotic prophylaxis changes all wound infections (SSSI + DSSI) ‐ low infection risk environment compared with placebo (very low certainty).
It is very uncertain whether antibiotic prophylaxis changes all wound infections (SSSI + DSSI) ‐ high infection risk environment compared with placebo (very low certainty).
Antibiotic prophylaxis probably leads to lower SSSI compared with placebo (moderate certainty).
Antibiotic prophylaxis showed no clear difference in SSSI ‐ low infection risk environment compared with placebo (moderate certainty).
It is very uncertain whether antibiotic prophylaxis changes SSSI ‐ high infection risk environment compared with placebo (very low certainty).
It is very uncertain whether summary of findings table ‐ Combined mechanical and oral antibiotic… changes surgical site infections compared with oral antibiotics alone (very low certainty).
Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in anastomotic leakage compared with oral antibiotics alone (low certainty).