Recurrence of symptomatic UTI in children with VUR · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in recurrence of symptomatic UTI in children with VUR compared with placebo or no treatment (low certainty).
1 finding from 1 review
Recurrence of symptomatic UTI in children, in studies with adequate allocation concealment · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment probably leads to lower recurrence of symptomatic UTI in children, in studies with adequate… compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Repeat positive urine culture · children with previous UTI and most do not have a renal tract abnormality such as VUR
It is very uncertain whether antibiotic treatment changes repeat positive urine culture compared with placebo or no treatment (very low certainty).
1 finding from 1 review
All adverse events · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in all adverse events compared with placebo or no treatment (low certainty).
1 finding from 1 review
Microbial resistance to prophylactic drug · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in microbial resistance to prophylactic drug compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Neonatal death rate due congenital syphilis · newborns with congenital syphilis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Neonatal mortality · newborns with congenital syphilis
Antibiotic treatment showed no clear difference in neonatal death rate due any cause compared with no intervention (low certainty).
1 finding from 1 review
Absence of clinical manifestations of congenital syphilis during · newborns with congenital syphilis
Antibiotic treatment showed no clear difference in absence of clinical manifestations of congenital syphilis during compared with no intervention (low certainty).
1 finding from 1 review
Serious adverse events · newborns with congenital syphilis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serological cure (4‐fold decrease or greater in non‐treponemal tests titre) · newborns with congenital syphilis
Antibiotic treatment may leads to higher serological cure (≥ 4‐fold decrease in non‐treponemal tests titre) compared with no intervention (low certainty).
1 finding from 1 review
Minor adverse events · newborns with congenital syphilis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Withdrawals due to adverse events · people with atopic dermatitis
1 finding from 1 review
Minor adverse events not leading to withdrawal of treatment · people with atopic dermatitis
1 finding from 1 review
Global change in composite ratings scale EASI ranges from 0 to 72 with higher values indicating greater severity. · people with atopic dermatitis
1 finding from 1 review
No of participants in whom S. aureus was isolated · people with atopic dermatitis
Oral antibiotic showed no clear difference in no of participants in whom S. aureus was isolated compared with placebo (low certainty).
1 finding from 1 review
Global outcome (good or excellent improvement in symptoms or signs, or both) · people with atopic dermatitis
Oral antibiotic showed no clear difference in global outcome (good or excellent improvement in symptoms or signs,… compared with placebo (low certainty).
1 finding from 1 review
Change from baseline in quality of life IDQoL ranges from 0 to 30 with higher values indicating more impaired quality of life. · people with atopic dermatitis
1 finding from 1 review
Serological cure (4‐fold decrease or greater in non‐treponemal tests titre) · newborns with congenital syphilis
Antibiotic treatment (benzathine penicillin) showed no clear difference in serological cure (4‐fold decrease or greater in non‐treponemal tests… compared with any other antibiotic (procaine benzylpenicillin) (moderate certainty).
1 finding from 1 review
Minor adverse events · newborns with congenital syphilis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Neonatal death rate due congenital syphilis · newborns with congenital syphilis
1 finding from 1 review
no estimate extracted
0 participants
GRADE not reported