Suspected ototoxicity · people (of any age) with CSOM
It is very uncertain whether systemic antibiotics changes suspected ototoxicity ‐ measured at 10 days to 3 weeks compared with no treatment or placebo on top of topical antibiotics (very low certainty).
1 finding from 1 review
Resolution of ear discharge ‐ measured at 1 to 2 weeks · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life ‐ unclear · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
1 finding from 1 review
Ear pain (otalgia) or discomfort or local irritation · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Hearing ‐ unclear · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
1 finding from 1 review
Serious complications ‐ mastoid abscess measured at 12 weeks · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
It is very uncertain whether systemic antibiotics changes serious complications ‐ mastoid abscess measured at 12 weeks compared with no treatment or placebo on top of topical antibiotics (very low certainty).
1 finding from 1 review
Suspected ototoxicity · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Resolution of ear discharge ‐ measured at 1 to 2 weeks · people (of any age) with CSOM
Systemic antibiotics showed no clear difference in resolution of ear discharge ‐ measured at 1 to 2 weeks compared with no treatment or placebo on top of topical antibiotics (low certainty).
1 finding from 1 review
Resolution of ear discharge ‐ measured after 4 weeks · people (of any age) with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intrapartum fever needing treatment with antibiotics · women in the second or third trimester of pregnancy before labour and delivery
1 finding from 1 review
Absence of fever (degree‐hour) ‐ Clindamycin after D&C versus D&C during clindamycin · patients with treating septic abortion
1 finding from 1 review
Absence of fever (degree‐hour) ‐ Penicillin + chloramphenicol after D&C versus D&C during penicillin + chloramphenicol therapy) · patients with treating septic abortion
1 finding from 1 review
FVC (% predicted) Change from baseline · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
1 finding from 1 review
Time to next exacerbation · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Subjective improvement in symptoms at 1 month and 3 months · adult participants with chronic blepharitis
1 finding from 1 review
Measurements of eradication or decrease in numbers of colonies of positive cultures of bacteria · adult participants with chronic blepharitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Clinical signs—Schirmer test scores at 1 month (mm/5 min) · adult participants with chronic blepharitis
1 finding from 1 review
Clinical signs—TBUT at 1 month (seconds) · adult participants with chronic blepharitis
1 finding from 1 review
Adverse events at 1 month · adult participants with chronic blepharitis
It is very uncertain whether oral antibiotics changes adverse events at 1 month compared with placebo (very low certainty).
1 finding from 1 review