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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
302 questions in 48 reviews · Neuromuscular
current versionsNo studies 302 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Surgery vs corticosteroid injection Health‐related quality of life ‐ Long‐term improvement: > 3 months · people with carpal tunnel syndrome Surgical versus non‐surgical treatment for carpal tunnel syndrome (2024) · Cochrane | no estimate extracted | NR | No studies |
Surgery vs splint Pain ‐ Long‐term improvement: > 3 months · people with carpal tunnel syndrome Surgical versus non‐surgical treatment for carpal tunnel syndrome (2024) · Cochrane | no estimate extracted | NR | No studies |
Intravenous immunoglobulin vs prednisolone Change in mean disability score at 24 weeks or later · patients with CIDP Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy (2024) · Cochrane | no estimate extracted | NR | No studies |
Intravenous immunoglobulin vs plasma exchange Significant improvement in disability within 6 weeks · people with CIDP Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy (2024) · Cochrane | no estimate extracted | NR | No studies |
Intravenous immunoglobulin vs plasma exchange Change in mean disability score on Rankin scale · people with CIDP Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy (2024) · Cochrane | no estimate extracted | NR | No studies |
Intravenous immunoglobulin vs plasma exchange Change in mean disability score at 24 weeks or later · people with CIDP Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy (2024) · Cochrane | no estimate extracted | NR | No studies |
Alpha‐lipoic acid vs placebo Change in any validated quality of life score · people with DPN Alpha‐lipoic acid for diabetic peripheral neuropathy (2024) · Cochrane | no estimate extracted | NR | No studies |
Alpha‐lipoic acid vs placebo Complications of DPN · people with DPN Alpha‐lipoic acid for diabetic peripheral neuropathy (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: plantar‐incision neurectomy (PN) vs dorsal‐incision neurectomy (DN) Pain: VAS(0 to 100; lower score indicates less pain) · Morton's neuroma Treatments for Morton's neuroma (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: plantar‐incision neurectomy (PN) vs dorsal‐incision neurectomy (DN) Function: restrictions in daily activities (4‐item Likert scale) · Morton's neuroma Treatments for Morton's neuroma (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: plantar‐incision neurectomy (PN) vs dorsal‐incision neurectomy (DN) HRQoL · Morton's neuroma Treatments for Morton's neuroma (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) vs non‐ultrasound‐guided injection of corticosteroid and local anaesthetic (NUG CS+LA) HRQoL · Morton's neuroma Treatments for Morton's neuroma (2024) · Cochrane | no estimate extracted | NR | No studies |
IVIg vs placebo Induction · people with multifocal motor neuropathy Immunoglobulin for multifocal motor neuropathy (2022) · Cochrane | no estimate extracted | NR | No studies |
IVIg vs SCIg Induction · people with multifocal motor neuropathy Immunoglobulin for multifocal motor neuropathy (2022) · Cochrane | no estimate extracted | NR | No studies |
IVIg vs SCIg Maintenance · people with multifocal motor neuropathy Immunoglobulin for multifocal motor neuropathy (2022) · Cochrane | no estimate extracted | NR | No studies |
IVIg vs SCIg Proportion of IVIg‐treated participants with an increase in disability during controlled IVIg withdrawal · people with multifocal motor neuropathy Immunoglobulin for multifocal motor neuropathy (2022) · Cochrane | no estimate extracted | NR | No studies |
IVIg vs SCIg Adverse events · people with multifocal motor neuropathy Immunoglobulin for multifocal motor neuropathy (2022) · Cochrane | no estimate extracted | NR | No studies |
IVIg vs placebo Proportion of participants with an improvement in disability at 12 months or later · people with multifocal motor neuropathy Immunoglobulin for multifocal motor neuropathy (2022) · Cochrane | no estimate extracted | NR | No studies |
IVIg vs placebo Maintenance · people with multifocal motor neuropathy Immunoglobulin for multifocal motor neuropathy (2022) · Cochrane | no estimate extracted | NR | No studies |
Dextromethorphan and quinidine sulfate combination (DMQ) vs placebo Quality of life · sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis (2022) · Cochrane | no estimate extracted | NR | No studies |
Scopolamine (hyoscine) patches vs placebo Quality of life · people with motor neuron disease/amyotrophic lateral sclerosis with sialorrhea (excessive saliva) (all fed via… Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis (2022) · Cochrane | no estimate extracted | NR | No studies |
Radiotherapy vs botulinum toxin Reduction in the amount of saliva production in the short term using an objective measure · people with motor neuron disease/amyotrophic lateral sclerosis with excessive saliva Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis (2022) · Cochrane | no estimate extracted | NR | No studies |
Radiotherapy vs botulinum toxin Quality of life · people with motor neuron disease/amyotrophic lateral sclerosis with excessive saliva Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis (2022) · Cochrane | no estimate extracted | NR | No studies |
Bioengineered devices vs standard techniques Muscle strength at ≥ 24 months · people undergoing peripheral nerve repair of the upper limb Bioengineered nerve conduits and wraps for peripheral nerve repair of the upper limb (2022) · Cochrane | no estimate extracted | NR | No studies |
Bioengineered devices vs standard techniques Impact on daily living · people undergoing peripheral nerve repair of the upper limb Bioengineered nerve conduits and wraps for peripheral nerve repair of the upper limb (2022) · Cochrane | no estimate extracted | NR | No studies |
Calf stretching vs placebo stretching Cramp severity · older adults with lower limb muscle cramps Non‐drug therapies for the secondary prevention of lower limb muscle cramps (2021) · Cochrane | no estimate extracted | NR | No studies |
Calf stretching vs placebo stretching Proportion of participants experiencing cramps · older adults with lower limb muscle cramps Non‐drug therapies for the secondary prevention of lower limb muscle cramps (2021) · Cochrane | no estimate extracted | NR | No studies |
Calf stretching vs placebo stretching Health‐related quality of life · older adults with lower limb muscle cramps Non‐drug therapies for the secondary prevention of lower limb muscle cramps (2021) · Cochrane | no estimate extracted | NR | No studies |
Calf stretching vs placebo stretching Quality of sleep · older adults with lower limb muscle cramps Non‐drug therapies for the secondary prevention of lower limb muscle cramps (2021) · Cochrane | no estimate extracted | NR | No studies |
Calf stretching vs placebo stretching Activities of daily living · older adults with lower limb muscle cramps Non‐drug therapies for the secondary prevention of lower limb muscle cramps (2021) · Cochrane | no estimate extracted | NR | No studies |
Calf, quadriceps, and hamstring stretching vs no stretching Proportion of participants experiencing cramps · 50‐ to 60‐year‐old women with metabolic syndrome Non‐drug therapies for the secondary prevention of lower limb muscle cramps (2021) · Cochrane | no estimate extracted | NR | No studies |
Calf, quadriceps, and hamstring stretching vs no stretching Health‐related quality of life · 50‐ to 60‐year‐old women with metabolic syndrome Non‐drug therapies for the secondary prevention of lower limb muscle cramps (2021) · Cochrane | no estimate extracted | NR | No studies |
Calf, quadriceps, and hamstring stretching vs no stretching Quality of sleep · 50‐ to 60‐year‐old women with metabolic syndrome Non‐drug therapies for the secondary prevention of lower limb muscle cramps (2021) · Cochrane | no estimate extracted | NR | No studies |
Calf, quadriceps, and hamstring stretching vs no stretching Activities of daily living · 50‐ to 60‐year‐old women with metabolic syndrome Non‐drug therapies for the secondary prevention of lower limb muscle cramps (2021) · Cochrane | no estimate extracted | NR | No studies |
Calf and hamstring stretching vs no intervention Proportion of participants experiencing cramps · older adults with lower limb muscle cramps Non‐drug therapies for the secondary prevention of lower limb muscle cramps (2021) · Cochrane | no estimate extracted | NR | No studies |
Calf and hamstring stretching vs no intervention Health‐related quality of life · older adults with lower limb muscle cramps Non‐drug therapies for the secondary prevention of lower limb muscle cramps (2021) · Cochrane | no estimate extracted | NR | No studies |
Calf and hamstring stretching vs no intervention Quality of sleep · older adults with lower limb muscle cramps Non‐drug therapies for the secondary prevention of lower limb muscle cramps (2021) · Cochrane | no estimate extracted | NR | No studies |
Calf and hamstring stretching vs no intervention Activities of daily living · older adults with lower limb muscle cramps Non‐drug therapies for the secondary prevention of lower limb muscle cramps (2021) · Cochrane | no estimate extracted | NR | No studies |
Cough augmentation therapy vs an alternative cough augmentation technique or combination of techniques Number of unscheduled hospital admissions for 'maintenance therapy' · participants with chronic neuromuscular diseases Cough augmentation techniques for people with chronic neuromuscular disorders (2021) · Cochrane | no estimate extracted | NR | No studies |
Cough augmentation therapy vs standard care Peak cough flow for 'rescue' or 'maintenance' therapy · participants with chronic neuromuscular diseases Cough augmentation techniques for people with chronic neuromuscular disorders (2021) · Cochrane | no estimate extracted | NR | No studies |
Cough augmentation therapy vs standard care Participant preference or satisfaction for 'rescue' or 'maintenance' therapy · participants with chronic neuromuscular diseases Cough augmentation techniques for people with chronic neuromuscular disorders (2021) · Cochrane | no estimate extracted | NR | No studies |
Cough augmentation therapy vs an alternative cough augmentation technique or combination of techniques Duration of hospital stay (days) for 'rescue' therapy · participants with chronic neuromuscular diseases Cough augmentation techniques for people with chronic neuromuscular disorders (2021) · Cochrane | no estimate extracted | NR | No studies |
Cough augmentation therapy vs an alternative cough augmentation technique or combination of techniques Quality of life for 'maintenance' therapy · participants with chronic neuromuscular diseases Cough augmentation techniques for people with chronic neuromuscular disorders (2021) · Cochrane | no estimate extracted | NR | No studies |
Cough augmentation therapy vs an alternative cough augmentation technique or combination of techniques Participant preference or satisfaction for 'rescue' and 'maintenance' therapy · participants with chronic neuromuscular diseases Cough augmentation techniques for people with chronic neuromuscular disorders (2021) · Cochrane | no estimate extracted | NR | No studies |
Cough augmentation therapy vs standard care Number of unscheduled hospital admissions for 'maintenance' therapy · participants with chronic neuromuscular diseases Cough augmentation techniques for people with chronic neuromuscular disorders (2021) · Cochrane | no estimate extracted | NR | No studies |
Cough augmentation therapy vs standard care Duration of hospital stay (days) for 'rescue' therapy · participants with chronic neuromuscular diseases Cough augmentation techniques for people with chronic neuromuscular disorders (2021) · Cochrane | no estimate extracted | NR | No studies |
Cough augmentation therapy vs standard care Quality of life for 'maintenance' therapy · participants with chronic neuromuscular diseases Cough augmentation techniques for people with chronic neuromuscular disorders (2021) · Cochrane | no estimate extracted | NR | No studies |
A functional programme vs a stretching programme Adverse events/serious adverse events · people with NMD Interventions for promoting physical activity in people with neuromuscular disease (2021) · Cochrane | no estimate extracted | NR | No studies |
A physical activity programme (weight‐bearing) vs no physical activity programme Quality of life · people with NMD Interventions for promoting physical activity in people with neuromuscular disease (2021) · Cochrane | no estimate extracted | NR | No studies |
A physical activity programme (weight‐bearing) vs no physical activity programme Adverse events/serious adverse events · people with NMD Interventions for promoting physical activity in people with neuromuscular disease (2021) · Cochrane | no estimate extracted | NR | No studies |