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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

303 questions in 64 reviews · Hepato-Biliary

current versions
No studies 303 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Microwave coagulation in addition to conventional transarterial chemoembolisation vs conventional transarterial chemoembolisation alone
All‐cause mortality · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation vs conventional surgery
Health‐related quality of life · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation vs conventional surgery
Failure to clear liver metastases · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation vs conventional surgery
Recurrence of liver metastases · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation vs radiofrequency ablation
Health‐related quality of life · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation vs radiofrequency ablation
Disease‐free survival · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation in addition to conventional transarterial chemoembolisation vs conventional transarterial chemoembolisation alone
Time to mortality · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation in addition to conventional transarterial chemoembolisation vs conventional transarterial chemoembolisation alone
Health‐related quality of life · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation in addition to conventional transarterial chemoembolisation vs conventional transarterial chemoembolisation alone
Disease‐free survival · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation in addition to conventional transarterial chemoembolisation vs conventional transarterial chemoembolisation alone
Failure to clear liver metastases · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Microwave coagulation in addition to conventional transarterial chemoembolisation vs conventional transarterial chemoembolisation alone
Recurrence of liver metastases · people with liver metastases
Microwave coagulation for liver metastases (2024) · Cochrane
no estimate extractedNRNo studies
Transjugular intrahepatic portosystemic shunts vs conventional treatment
Health‐related quality of life · adults with hepatorenal syndrome
Transjugular intrahepatic portosystemic shunts for adults with hepatorenal syndrome (2024) · Cochrane
no estimate extractedNRNo studies
Intervention NR
All‐cause mortality · participants with gallstone disease (cholesterol, pigment, or mixed)
Modified dietary fat intake for treatment of gallstone disease in people of any age (2024) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Serious adverse events at longest · participants with gallstone disease (cholesterol, pigment, or mixed)
Modified dietary fat intake for treatment of gallstone disease in people of any age (2024) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Health‐related quality of life · participants with gallstone disease (cholesterol, pigment, or mixed)
Modified dietary fat intake for treatment of gallstone disease in people of any age (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs shallow NMB
All‐cause mortality ‐ not reported · adults undergoing intra‐ and transperitoneal laparoscopic procedures
Deep neuromuscular blockade in adults undergoing an abdominal laparoscopic procedure (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs shallow NMB
Health‐related quality of life ‐ not reported · adults undergoing intra‐ and transperitoneal laparoscopic procedures
Deep neuromuscular blockade in adults undergoing an abdominal laparoscopic procedure (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs no NMB
All‐cause mortality start of surgery ‐ not reported · adults undergoing intra‐ and transperitoneal laparoscopic procedures
Deep neuromuscular blockade in adults undergoing an abdominal laparoscopic procedure (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs no NMB
Health‐related quality of life ‐ not reported · adults undergoing intra‐ and transperitoneal laparoscopic procedures
Deep neuromuscular blockade in adults undergoing an abdominal laparoscopic procedure (2024) · Cochrane
no estimate extractedNRNo studies
Double‐dose adenovirus‐thymidine kinase with ganciclovir (ADV‐TK/GCV) plus liver transplantation vs liver transplantation
Proportion of people with ≥ 1 serious adverse events during treatment · participants with unresectable hepatocellular carcinoma
Gene therapy for people with hepatocellular carcinoma (2024) · Cochrane
no estimate extractedNRNo studies
Double‐dose adenovirus‐thymidine kinase with ganciclovir (ADV‐TK/GCV) plus liver transplantation vs liver transplantation
Health‐related quality of life · participants with unresectable hepatocellular carcinoma
Gene therapy for people with hepatocellular carcinoma (2024) · Cochrane
no estimate extractedNRNo studies
Double‐dose adenovirus‐thymidine kinase with ganciclovir (ADV‐TK/GCV) plus liver transplantation vs liver transplantation
Proportion of people with disease progression · participants with unresectable hepatocellular carcinoma
Gene therapy for people with hepatocellular carcinoma (2024) · Cochrane
no estimate extractedNRNo studies
Double‐dose adenovirus‐thymidine kinase with ganciclovir (ADV‐TK/GCV) plus liver transplantation vs liver transplantation
Adverse events considered non‐serious · participants with unresectable hepatocellular carcinoma
Gene therapy for people with hepatocellular carcinoma (2024) · Cochrane
no estimate extractedNRNo studies
Recombinant human adenovirus‐p53 and hydroxycamptothecin (rAd‐p53/HCT) vs hydroxycamptothecin
Proportion of people with ≥ 1 serious adverse events · participants with unresectable hepatocellular carcinoma
Gene therapy for people with hepatocellular carcinoma (2024) · Cochrane
no estimate extractedNRNo studies
Recombinant human adenovirus‐p53 and hydroxycamptothecin (rAd‐p53/HCT) vs hydroxycamptothecin
Health‐related quality of life · participants with unresectable hepatocellular carcinoma
Gene therapy for people with hepatocellular carcinoma (2024) · Cochrane
no estimate extractedNRNo studies
Recombinant human adenovirus‐p53 and 5‐fluorouracil (rAd‐p53/5‐Fu) plus transarterial chemoembolisation vs transarterial chemoembolisation
Overall survival · participants with unresectable hepatocellular carcinoma
Gene therapy for people with hepatocellular carcinoma (2024) · Cochrane
no estimate extractedNRNo studies
Recombinant human adenovirus‐p53 and 5‐fluorouracil (rAd‐p53/5‐Fu) plus transarterial chemoembolisation vs transarterial chemoembolisation
Proportion of people with ≥ 1 serious adverse events · participants with unresectable hepatocellular carcinoma
Gene therapy for people with hepatocellular carcinoma (2024) · Cochrane
no estimate extractedNRNo studies
Recombinant human adenovirus‐p53 and 5‐fluorouracil (rAd‐p53/5‐Fu) plus transarterial chemoembolisation vs transarterial chemoembolisation
Health‐related quality of life · participants with unresectable hepatocellular carcinoma
Gene therapy for people with hepatocellular carcinoma (2024) · Cochrane
no estimate extractedNRNo studies
Recombinant human adenovirus‐p53 and 5‐fluorouracil (rAd‐p53/5‐Fu) plus transarterial chemoembolisation vs transarterial chemoembolisation
Adverse events considered non‐serious (number of events) · participants with unresectable hepatocellular carcinoma
Gene therapy for people with hepatocellular carcinoma (2024) · Cochrane
no estimate extractedNRNo studies
E1B‐deleted (dl1520) adenovirus vs percutaneous ethanol injection
Overall survival · participants with unresectable hepatocellular carcinoma
Gene therapy for people with hepatocellular carcinoma (2024) · Cochrane
no estimate extractedNRNo studies
E1B‐deleted (dl1520) adenovirus vs percutaneous ethanol injection
Proportion of people with ≥ 1 serious adverse events · participants with unresectable hepatocellular carcinoma
Gene therapy for people with hepatocellular carcinoma (2024) · Cochrane
no estimate extractedNRNo studies
E1B‐deleted (dl1520) adenovirus vs percutaneous ethanol injection
Health‐related quality of life · participants with unresectable hepatocellular carcinoma
Gene therapy for people with hepatocellular carcinoma (2024) · Cochrane
no estimate extractedNRNo studies
Adenovirus‐thymidine kinase with ganciclovir (ADV‐TK/GCV) plus liver transplantation vs liver transplantation
Proportion of people with ≥ 1 serious adverse events during treatment · participants with unresectable hepatocellular carcinoma
Gene therapy for people with hepatocellular carcinoma (2024) · Cochrane
no estimate extractedNRNo studies
Adenovirus‐thymidine kinase with ganciclovir (ADV‐TK/GCV) plus liver transplantation vs liver transplantation
Health‐related quality of life · participants with unresectable hepatocellular carcinoma
Gene therapy for people with hepatocellular carcinoma (2024) · Cochrane
no estimate extractedNRNo studies
Adenovirus‐thymidine kinase with ganciclovir (ADV‐TK/GCV) plus liver transplantation vs liver transplantation
Proportion of people with disease progression · participants with unresectable hepatocellular carcinoma
Gene therapy for people with hepatocellular carcinoma (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Endoscopic sphincterotomy vs endoscopic papillary balloon dilation
All‐cause mortality (or overall survival) ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Endoscopic sphincterotomy vs endoscopic papillary balloon dilation
Proportion of participants with ≥ 1 non‐serious adverse events ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Biliary endoscopic sphincterotomy vs dual endoscopic sphincterotomy
Proportion of participants with ≥ 1 serious adverse events ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Biliary endoscopic sphincterotomy vs dual endoscopic sphincterotomy
Health‐related quality of life ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Biliary endoscopic sphincterotomy vs dual endoscopic sphincterotomy
All‐cause mortality (or overall survival) ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Biliary endoscopic sphincterotomy vs dual endoscopic sphincterotomy
Proportion of participants with ≥ 1 non‐serious adverse events ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Endoscopic sphincterotomy vs sham treatment
All‐cause mortality (or overall survival) ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Endoscopic sphincterotomy vs sham treatment
Proportion of participants with ≥ 1 non‐serious adverse events ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Endoscopic sphincterotomy vs endoscopic papillary balloon dilation
Proportion of participants without successful treatment ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Endoscopic sphincterotomy vs endoscopic papillary balloon dilation
Health‐related quality of life ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Antibiotics vs other antibiotics
Serious adverse events ‐ not reported · farmworkers
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Antibiotics vs other antibiotics
Quality of life ‐ not reported · farmworkers
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Antibiotics vs placebo or no intervention
Serious adverse events ‐ not reported · farmworkers, soldiers, and people in endemic areas
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Antibiotics vs placebo or no intervention
Quality of life ‐ not reported · farmworkers, soldiers, and people in endemic areas
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Antibiotics vs other antibiotics
All‐cause mortality ‐ not reported · farmworkers
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
no estimate extractedNRNo studies