Cochrane · systematic review · CD011039

Transjugular intrahepatic portosystemic shunts for adults with hepatorenal syndrome

Gonzalez-Garay, AG, Serralde-Zúñiga, AE, Velasco Hidalgo, L, et al. · Cochrane Database of Systematic Reviews · 2024 · Cochrane Library

Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 4 · 57.1%Low 2 · 28.6%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Transjugular intrahepatic portosystemic shunts compared with conventional treatment for hepatorenal syndrome

Population: adults with hepatorenal syndrome
7 questions
OutcomeEffectEvidenceStatus / GRADE
All‐cause mortality
Transjugular intrahepatic portosystemic shunts vs conventional treatment
RR 0.88 [0.55, 1.38]2 studies · 130 participantsVery low
Downgraded: risk of bias, inconsistency
Morbidity due to any cause
Transjugular intrahepatic portosystemic shunts vs conventional treatment
RR 0.95 [0.77, 1.18]2 studies · 130 participantsLow
Downgraded: risk of bias, imprecision
Serious adverse events
Transjugular intrahepatic portosystemic shunts vs conventional treatment
RR 1.6 [0.1, 24.59]2 studies · 130 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Health‐related quality of life
Transjugular intrahepatic portosystemic shunts vs conventional treatment
no estimate extractedNRNo studies
Participants who did not receive a liver transplant
Transjugular intrahepatic portosystemic shunts vs conventional treatment
RR 1.03 [0.93, 1.14]2 studies · 130 participantsVery low
Downgraded: risk of bias, imprecision
Participants without improvement in kidney function
Transjugular intrahepatic portosystemic shunts vs conventional treatment
RR 0.53 [0.27, 1.02]1 study · 70 participantsLow
Downgraded: risk of bias, imprecision
Length of hospitalisation measured in days
Transjugular intrahepatic portosystemic shunts vs conventional treatment
no estimate extracted1 study · 60 participantsVery low
Downgraded: risk of bias, imprecision