Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

15,213 questions in 2,394 reviews

current versions
No studies 15,213 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo plus usual pharmacological care
Disease activity ‐ not measured · systemic lupus erythematosus
Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo plus usual pharmacological care
Quality of life ‐ not measured · systemic lupus erythematosus
Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo plus usual pharmacological care
Serious adverse events ‐ not reported · systemic lupus erythematosus
Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane
no estimate extractedNRNo studies
Cognitive behavioural therapy manual and telephone support vs usual care
Disease activity · people with inflammatory bowel disease
Remote care through telehealth for people with inflammatory bowel disease (2023) · Cochrane
no estimate extractedNRNo studies
Cognitive behavioural therapy manual and telephone support vs usual care
Flare‐ups/relapse · people with inflammatory bowel disease
Remote care through telehealth for people with inflammatory bowel disease (2023) · Cochrane
no estimate extractedNRNo studies
Cognitive behavioural therapy manual and telephone support vs usual care
Quality of life · people with inflammatory bowel disease
Remote care through telehealth for people with inflammatory bowel disease (2023) · Cochrane
no estimate extractedNRNo studies
Web‐based disease monitoring vs sham monitoring
Disease activity · people with inflammatory bowel disease
Remote care through telehealth for people with inflammatory bowel disease (2023) · Cochrane
no estimate extractedNRNo studies
Web‐based disease monitoring vs sham monitoring
Flare‐ups/relapse · people with inflammatory bowel disease
Remote care through telehealth for people with inflammatory bowel disease (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Finding 6. Patients, caregivers, and providers described a number of privacy and confidentiality issues when services were provided at home. These included the increased privacy of being able to exercise at home but also the loss of privacy when e...
Factors that influence the provision of home‐based rehabilitation services for people needing… (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Finding 7. Patients regarded in‐person home‐based rehabilitation and telerehabilitation services as convenient and less disruptive of everyday activities.
Factors that influence the provision of home‐based rehabilitation services for people needing… (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Finding 9. Healthcare providers highlighted the importance of personalising the service to each patient’s needs and resources at home.
Factors that influence the provision of home‐based rehabilitation services for people needing… (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Finding 10. Patients, caregivers, healthcare providers and other stakeholders described how telerehabilitation changed the nature of the patient‐provider relationship. This included overcoming physical barriers to communication and enabling quick ...
Factors that influence the provision of home‐based rehabilitation services for people needing… (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Finding 11. Healthcare providers and patients described some aspects of telerehabilitation services at home as challenging. Healthcare providers described problems in assessing patients, their environment, and whether they were performing exercise...
Factors that influence the provision of home‐based rehabilitation services for people needing… (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Finding 12. Patients, caregivers, healthcare providers and other stakeholders regarded telerehabilitation as an opportunity to make rehabilitation services more accessible.
Factors that influence the provision of home‐based rehabilitation services for people needing… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Psychological interventions vs inactive control (usual care care, attention control, waitlist)
Parental self‐harm ‐ post‐intervention ‐ not reported · parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood
Interventions from pregnancy to two years after birth for parents experiencing complex post‐traumatic stress… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Service system approaches vs inactive control (usual care care, attention control, waitlist)
Trauma‐related symptoms ‐ post‐intervention ‐ not reported · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood
Interventions from pregnancy to two years after birth for parents experiencing complex post‐traumatic stress… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Service system approaches vs inactive control (usual care care, attention control, waitlist)
Substance use ‐ post‐intervention ‐ not reported · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood
Interventions from pregnancy to two years after birth for parents experiencing complex post‐traumatic stress… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Service system approaches vs inactive control (usual care care, attention control, waitlist)
Parent relationship quality ‐ not reported · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood
Interventions from pregnancy to two years after birth for parents experiencing complex post‐traumatic stress… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Service system approaches vs inactive control (usual care care, attention control, waitlist)
Parental self‐harm ‐ post‐intervention ‐ not reported · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood
Interventions from pregnancy to two years after birth for parents experiencing complex post‐traumatic stress… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Service system approaches vs inactive control (usual care care, attention control, waitlist)
Parent–child relationship ‐ not reported · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood
Interventions from pregnancy to two years after birth for parents experiencing complex post‐traumatic stress… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Service system approaches vs inactive control (usual care care, attention control, waitlist)
Parenting skills ‐ post‐intervention ‐ not reported · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood
Interventions from pregnancy to two years after birth for parents experiencing complex post‐traumatic stress… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Parenting interventions vs inactive control (usual care care, attention control, waitlist)
Substance use ‐ post‐intervention ‐ not reported · parents who are experiencing CPTSD symptoms or have experienced maltreatment in childhood
Interventions from pregnancy to two years after birth for parents experiencing complex post‐traumatic stress… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Parenting interventions vs inactive control (usual care care, attention control, waitlist)
Parent relationship quality ‐ post‐intervention ‐ not reported · parents who are experiencing CPTSD symptoms or have experienced maltreatment in childhood
Interventions from pregnancy to two years after birth for parents experiencing complex post‐traumatic stress… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Parenting interventions vs inactive control (usual care care, attention control, waitlist)
Parental self‐harm ‐ post‐intervention ‐ not reported · parents who are experiencing CPTSD symptoms or have experienced maltreatment in childhood
Interventions from pregnancy to two years after birth for parents experiencing complex post‐traumatic stress… (2023) · Cochrane
no estimate extractedNRNo studies
Tramadol vs no treatment or placebo
Pain · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Fentanyl vs tramadol
Major neurodevelopmental disability in children aged three to five years · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Fentanyl vs tramadol
Cognitive and educational outcomes in children more than five years old · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Fentanyl vs tramadol
Severe retinopathy of prematurity (defined as stage 3 or greater) · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Fentanyl vs tramadol
Severe intraventricular hemorrhage (grade 3 or greater) on cranial ultrasound, as per Papile classification · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Morphine vs paracetamol
Major neurodevelopmental disability in children aged 18 to 24 months · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Morphine vs paracetamol
Major neurodevelopmental disability in children aged three to five years · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Morphine vs paracetamol
Cognitive and educational outcomes in children more than five years old · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Morphine vs paracetamol
All‐cause mortality during initial hospitalization · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Tramadol vs no treatment or placebo
Major neurodevelopmental disability in children aged 18 to 24 months · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Morphine vs paracetamol
Severe retinopathy of prematurity (defined as stage 3 or greater) · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Morphine vs paracetamol
Severe intraventricular hemorrhage (grade 3 or greater) on cranial ultrasound, as per Papile classification · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Tramadol vs no treatment or placebo
Major neurodevelopmental disability in children aged three to five years · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Tramadol vs no treatment or placebo
Cognitive and educational outcomes in children more than five years old · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Tramadol vs no treatment or placebo
Severe retinopathy of prematurity (defined as stage 3 or greater) · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Tramadol vs no treatment or placebo
Severe intraventricular hemorrhage (grade 3 or greater) on cranial ultrasound, as per Papile classification · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Fentanyl vs tramadol
Pain · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Fentanyl vs tramadol
Major neurodevelopmental disability in children aged 18 to 24 months · postoperative pain in preterm and term infants
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Primary treatment with intravenous immunoglobulin (IVIG) vs different infusion regimens of IVIG
Acute coronary syndrome (such as MI or coronary thrombus) (up to 7 weeks) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
no estimate extractedNRNo studies
Primary treatment with intravenous immunoglobulin (IVIG) vs prednisolone
Need for additional treatment · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
no estimate extractedNRNo studies
Primary treatment with intravenous immunoglobulin (IVIG) vs prednisolone
Length of hospital stay (days) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
no estimate extractedNRNo studies
Primary treatment with intravenous immunoglobulin (IVIG) vs acetylsalicylic acid (ASA)
Length of hospital stay (days) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Any type of hormonal contraception (estrogen plus progestin or progestin‐only) vs no contraception
Venous thromboembolism ‐ not measured · COVID‐19 positive patients
Risk of thromboembolism in patients with COVID‐19 who are using hormonal contraception (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Any type of hormonal contraception (estrogen plus progestin or progestin‐only) vs no contraception
Arterial thromboembolism ‐ not measured · COVID‐19 positive patients
Risk of thromboembolism in patients with COVID‐19 who are using hormonal contraception (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Any type of hormonal contraception (estrogen plus progestin or progestin‐only) vs no contraception
Acute respiratory distress syndrome ‐ not measured · COVID‐19 positive patients
Risk of thromboembolism in patients with COVID‐19 who are using hormonal contraception (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Combined hormonal contraception (estrogen plus progestin) vs no contraception
Arterial thromboembolism ‐ not measured · COVID‐19 positive patients
Risk of thromboembolism in patients with COVID‐19 who are using hormonal contraception (2023) · Cochrane
no estimate extractedNRNo studies