Cochrane · systematic review · CD014908

Risk of thromboembolism in patients with COVID‐19 who are using hormonal contraception

Ramanadhan, S, Hansen, K, Henderson, JT, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

Fertility Regulation2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
6
No studies
6
Included studies
NR
No studies 6 · 50%Ungraded 0 · 0%Very low 6 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Summary of findings table ‐ Combined hormonal contraception (estrogen plus progestin) compared to no contraception for COVID‐19 positive patients

Population: COVID‐19 positive patients
6 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality
Summary of findings table ‐ Combined hormonal contraception (estrogen plus progestin) vs no contraception
OR 1 [0.41, 2.4]1 study · 18892 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Hospitalization
Summary of findings table ‐ Combined hormonal contraception (estrogen plus progestin) vs no contraception
OR 0.79 [0.64, 0.97]1 study · 295689 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Venous thromboembolism
Summary of findings table ‐ Combined hormonal contraception (estrogen plus progestin) vs no contraception
no estimate extracted2 studies · 13 participantsVery low
Downgraded: risk of bias, imprecision
Intubation
Summary of findings table ‐ Combined hormonal contraception (estrogen plus progestin) vs no contraception
no estimate extracted1 study · 7 participantsVery low
Downgraded: risk of bias, imprecision
Arterial thromboembolism ‐ not measured
Summary of findings table ‐ Combined hormonal contraception (estrogen plus progestin) vs no contraception
no estimate extractedNRNo studies
Acute respiratory distress syndrome ‐ not measured
Summary of findings table ‐ Combined hormonal contraception (estrogen plus progestin) vs no contraception
no estimate extractedNRNo studies

Summary of findings table ‐ Any type of hormonal contraception (estrogen plus progestin or progestin‐only) compared to no contraception for COVID‐19 positive patients

Population: COVID‐19 positive patients
6 questions
OutcomeEffectEvidenceStatus / GRADE
Hospitalization
Summary of findings table ‐ Any type of hormonal contraception (estrogen plus progestin or progestin‐only) vs no contraception
OR 0.99 [0.68, 1.44]1 study · 123 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Intubation
Summary of findings table ‐ Any type of hormonal contraception (estrogen plus progestin or progestin‐only) vs no contraception
no estimate extracted1 study · 123 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Mortality ‐ not measured
Summary of findings table ‐ Any type of hormonal contraception (estrogen plus progestin or progestin‐only) vs no contraception
no estimate extractedNRNo studies
Venous thromboembolism ‐ not measured
Summary of findings table ‐ Any type of hormonal contraception (estrogen plus progestin or progestin‐only) vs no contraception
no estimate extractedNRNo studies
Arterial thromboembolism ‐ not measured
Summary of findings table ‐ Any type of hormonal contraception (estrogen plus progestin or progestin‐only) vs no contraception
no estimate extractedNRNo studies
Acute respiratory distress syndrome ‐ not measured
Summary of findings table ‐ Any type of hormonal contraception (estrogen plus progestin or progestin‐only) vs no contraception
no estimate extractedNRNo studies