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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

420 questions in 57 reviews · Gut

current versions
No studies 420 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Web‐based patient education vs other delivery of patient education
Flare‐ups or relapse (continuous) · people with inflammatory bowel disease
Patient education interventions for the management of inflammatory bowel disease (2023) · Cochrane
no estimate extractedNRNo studies
Web‐based patient education vs other delivery of patient education
Flare‐ups or relapse (dichotomous) · people with inflammatory bowel disease
Patient education interventions for the management of inflammatory bowel disease (2023) · Cochrane
no estimate extractedNRNo studies
Cognitive behavioural therapy manual and telephone support vs usual care
Disease activity · people with inflammatory bowel disease
Remote care through telehealth for people with inflammatory bowel disease (2023) · Cochrane
no estimate extractedNRNo studies
Cognitive behavioural therapy manual and telephone support vs usual care
Flare‐ups/relapse · people with inflammatory bowel disease
Remote care through telehealth for people with inflammatory bowel disease (2023) · Cochrane
no estimate extractedNRNo studies
Cognitive behavioural therapy manual and telephone support vs usual care
Quality of life · people with inflammatory bowel disease
Remote care through telehealth for people with inflammatory bowel disease (2023) · Cochrane
no estimate extractedNRNo studies
Web‐based disease monitoring vs sham monitoring
Disease activity · people with inflammatory bowel disease
Remote care through telehealth for people with inflammatory bowel disease (2023) · Cochrane
no estimate extractedNRNo studies
Web‐based disease monitoring vs sham monitoring
Flare‐ups/relapse · people with inflammatory bowel disease
Remote care through telehealth for people with inflammatory bowel disease (2023) · Cochrane
no estimate extractedNRNo studies
Tacrolimus vs ciclosporin
Serious adverse events · adults with refractory, moderate‐to‐severe ulcerative colitis
Tacrolimus (FK506) for induction of remission in corticosteroid‐refractory ulcerative colitis (2022) · Cochrane
no estimate extractedNRNo studies
Tacrolimus vs ciclosporin
Total adverse events · adults with refractory, moderate‐to‐severe ulcerative colitis
Tacrolimus (FK506) for induction of remission in corticosteroid‐refractory ulcerative colitis (2022) · Cochrane
no estimate extractedNRNo studies
LHC + Dor vs LHC + angle of His accentuation
Postoperative pathological acid reflux · adult patients (> 18 years) with achalasia
Fundoplication in laparoscopic Heller's cardiomyotomy for achalasia (2022) · Cochrane
no estimate extractedNRNo studies
Duct‐to‐mucosa pancreaticojejunostomy using the modified Blumgart technique vs duct‐to‐mucosa pancreaticojejunostomy using the traditional interrupted technique
Adverse events · adults undergoing open pancreaticoduodenectomy
Duct‐to‐mucosa versus other types of pancreaticojejunostomy for the prevention of postoperative pancreatic… (2022) · Cochrane
no estimate extractedNRNo studies
Duct‐to‐mucosa pancreaticojejunostomy using the modified Blumgart technique vs duct‐to‐mucosa pancreaticojejunostomy using the traditional interrupted technique
Quality of life · adults undergoing open pancreaticoduodenectomy
Duct‐to‐mucosa versus other types of pancreaticojejunostomy for the prevention of postoperative pancreatic… (2022) · Cochrane
no estimate extractedNRNo studies
Duct‐to‐mucosa vs invagination pancreaticojejunostomy
Adverse events · adults undergoing open pancreaticoduodenectomy
Duct‐to‐mucosa versus other types of pancreaticojejunostomy for the prevention of postoperative pancreatic… (2022) · Cochrane
no estimate extractedNRNo studies
Duct‐to‐mucosa vs invagination pancreaticojejunostomy
Quality of life · adults undergoing open pancreaticoduodenectomy
Duct‐to‐mucosa versus other types of pancreaticojejunostomy for the prevention of postoperative pancreatic… (2022) · Cochrane
no estimate extractedNRNo studies
Antibiotics vs probiotics
Failure to induce clinical response at end of study · people with active UC
Antibiotics for the induction and maintenance of remission in ulcerative colitis (2022) · Cochrane
no estimate extractedNRNo studies
Antibiotics vs 5‐ASA
Failure to maintain clinical response at end of study · people with UC in remission
Antibiotics for the induction and maintenance of remission in ulcerative colitis (2022) · Cochrane
no estimate extractedNRNo studies
Antibiotics vs no treatment
Failure to induce clinical response at end of study · of active and inactive people with ulcerative colitis
Antibiotics for the induction and maintenance of remission in ulcerative colitis (2022) · Cochrane
no estimate extractedNRNo studies
Antibiotics plus probiotics vs placebo or no intervention
Failure to induce clinical response at end of study · people with active UC
Antibiotics for the induction and maintenance of remission in ulcerative colitis (2022) · Cochrane
no estimate extractedNRNo studies
Antibiotics vs 5‐ASA
Failure to induce clinical remission at end of study · people with active UC
Antibiotics for the induction and maintenance of remission in ulcerative colitis (2022) · Cochrane
no estimate extractedNRNo studies
Synbiotics vs placebo
Frequency of defecation (number of stools/week at end of study) · children with chronic constipation without a physical explanation
Probiotics for treatment of chronic constipation in children (2022) · Cochrane
no estimate extractedNRNo studies
Early vs late drain removal following pancreatic surgery
Mortality · people undergoing elective pancreatic resections
Prophylactic abdominal drainage for pancreatic surgery (2021) · Cochrane
no estimate extractedNRNo studies
Early vs late drain removal following pancreatic surgery
Drain‐related complications · people undergoing elective pancreatic resections
Prophylactic abdominal drainage for pancreatic surgery (2021) · Cochrane
no estimate extractedNRNo studies
Active drain vs passive drain following pancreatic surgery
Mortality · people undergoing elective pancreatic resections
Prophylactic abdominal drainage for pancreatic surgery (2021) · Cochrane
no estimate extractedNRNo studies
Returning vs discarding the aspirated/drained gastric residual volume
Mortality (at the end of · adults receiving EN via nasogastric or gastrostomy tube
Monitoring of gastric residual volume during enteral nutrition (2021) · Cochrane
no estimate extractedNRNo studies
Returning vs discarding the aspirated/drained gastric residual volume
Pneumonia (at the end of · adults receiving EN via nasogastric or gastrostomy tube
Monitoring of gastric residual volume during enteral nutrition (2021) · Cochrane
no estimate extractedNRNo studies
Returning vs discarding the aspirated/drained gastric residual volume
Length of hospital stay (days) (at the end of · adults receiving EN via nasogastric or gastrostomy tube
Monitoring of gastric residual volume during enteral nutrition (2021) · Cochrane
no estimate extractedNRNo studies
IM erythropoietin vs oral placebo
Serious adverse events · IBD patients
Interventions for treating iron deficiency anaemia in inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Low FODMAP diet vs sham diet
Treatment success as defined by the authors · people with inflammatory bowel disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Medicine‐separated moxibustion combined with acupuncture vs wheat bran‐separated moxibustion combined with shallow acupuncture
Abdominal pain frequency or change in frequency · people with Crohn's disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Medicine‐separated moxibustion combined with acupuncture vs wheat bran‐separated moxibustion combined with shallow acupuncture
Abdominal pain intensity or change in intensity · people with Crohn's disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Mindfulness with cognitive behavioural therapy (CBT) vs no treatment (both groups received standard medical therapy)
Treatment success as defined by the authors · people with inflammatory bowel disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
soft non‐manipulative osteopathic treatment vs no intervention
Treatment success as defined by the authors · people with Crohn's disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
soft non‐manipulative osteopathic treatment vs no intervention
Abdominal pain frequency or change in frequency · people with Crohn's disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Directed stress management (it is unclear whether these interventions replaced standard treatment or were added to standard treatment) vs standard treatment
Treatment success as defined by the authors · people with Crohn's disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Directed stress management (it is unclear whether these interventions replaced standard treatment or were added to standard treatment) vs standard treatment
Pain frequency or change in pain frequency · people with Crohn's disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Directed stress management (it is unclear whether these interventions replaced standard treatment or were added to standard treatment) vs standard treatment
Withdrawals due to adverse events · people with Crohn's disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Self‐directed stress management (it is unclear whether these interventions replaced standard treatment or were added to standard treatment) vs standard treatment
Treatment success as defined by the authors · people with Crohn's disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Self‐directed stress management (it is unclear whether these interventions replaced standard treatment or were added to standard treatment) vs standard treatment
Pain frequency or change in pain frequency · people with Crohn's disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Self‐directed stress management (it is unclear whether these interventions replaced standard treatment or were added to standard treatment) vs standard treatment
Withdrawals due to adverse events · people with Crohn's disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Enteric‐release glyceryl trinitrate vs placebo
Treatment success as defined by the authors · people with Crohn's disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Enteric‐release glyceryl trinitrate vs placebo
Abdominal pain frequency or change in frequency · people with Crohn's disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Enteric‐release glyceryl trinitrate vs placebo
Abdominal pain intensity or change in intensity · people with Crohn's disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
100 mg olorinab 3 times/day vs 25 mg olorinab 3 times/day
Treatment success as defined by the authors · people with Crohn's disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
100 mg olorinab 3 times/day vs 25 mg olorinab 3 times/day
Pain frequency or change in pain frequency · people with Crohn's disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Relaxation training vs waitlist
Treatment success as defined by the authors · people with inflammatory bowel disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Relaxation training vs waitlist
Pain frequency or change in pain frequency · people with inflammatory bowel disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Relaxation training vs waitlist
Withdrawals due to adverse effects · people with inflammatory bowel disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Web‐based education vs standard book‐based education
Treatment success as defined by the authors · people with inflammatory bowel disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Web‐based education vs standard book‐based education
Abdominal pain frequency or change in frequency · people with inflammatory bowel disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies
Yoga intervention vs no treatment (both groups received standard medical therapy)
Treatment success as defined by the authors · people with inflammatory bowel disease
Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease (2021) · Cochrane
no estimate extractedNRNo studies