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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

15,213 questions in 2,394 reviews

current versions
No studies 15,213 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Vitrectomy vs observation
Costs · participants with idiopathic macular hole
Vitrectomy for idiopathic macular hole (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
OHSS ‐ short vs long protocol · subfertile women
Luteal phase support for assisted reproduction cycles (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
OHSS ‐ low vs high dose protocol · subfertile women
Luteal phase support for assisted reproduction cycles (2015) · Cochrane
no estimate extractedNRNo studies
Progesterone vs placebo/no treatment
OHSS · subfertile women
Luteal phase support for assisted reproduction cycles (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse events · Adults (including pregnant women) and children
Strategies to increase the ownership and use of insecticide‐treated bednets to prevent malaria (2015) · Cochrane
no estimate extractedNRNo studies
Helicopter emergency medical services vs ground emergency medical services
Quality‐adjusted life years · adults (age > 15 years) with major trauma (ISS > 15)
Helicopter emergency medical services for adults with major trauma (2015) · Cochrane
no estimate extractedNRNo studies
Helicopter emergency medical services vs ground emergency medical services
Disability‐adjusted life years · adults (age > 15 years) with major trauma (ISS > 15)
Helicopter emergency medical services for adults with major trauma (2015) · Cochrane
no estimate extractedNRNo studies
Helicopter emergency medical services vs ground emergency medical services
Adverse events · adults (age > 15 years) with major trauma (ISS > 15)
Helicopter emergency medical services for adults with major trauma (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Reduce hip migration/hip problems · Children with cerebral palsy
Sleep positioning systems for children with cerebral palsy (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Effect on quality of life of child and family · Children with cerebral palsy
Sleep positioning systems for children with cerebral palsy (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Effect on physical functioning · Children with cerebral palsy
Sleep positioning systems for children with cerebral palsy (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse effects · Children with cerebral palsy
Sleep positioning systems for children with cerebral palsy (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Heparin vs no treatment
Quality of life · People undergoing autologous or HLA identical allogeneic bone marrow transplant with a variety of malignant diseases…
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Low molecular weight heparin vs placebo or no treatment
Overall survival · People undergoing stem cell transplant with malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Low molecular weight heparin vs placebo or no treatment
All‐cause mortality at 100 days post‐transplant · People undergoing stem cell transplant with malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Low molecular weight heparin vs placebo or no treatment
Mortality attributable to hepatic veno‐occlusive disease · People undergoing stem cell transplant with malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Low molecular weight heparin vs placebo or no treatment
Quality of life · People undergoing stem cell transplant with malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Defibrotide vs no treatment
Quality of life · Children undergoing stem cell transplant with malignant and non‐malignant diseases and risk factors for hepatic…
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Glutamine vs placebo
Overall survival · People undergoing stem cell transplant with haematological malignancies
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Glutamine vs placebo
Quality of life · People undergoing stem cell transplant with haematological malignancies
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Fresh frozen plasma vs no treatment
Overall survival · People undergoing stem cell transplants with malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Fresh frozen plasma vs no treatment
All‐cause mortality at 100 days post‐transplant · People undergoing stem cell transplants with malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Fresh frozen plasma vs no treatment
Mortality attributable to hepatic veno‐occlusive disease · People undergoing stem cell transplants with malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Fresh frozen plasma vs no treatment
Quality of life · People undergoing stem cell transplants with malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Fresh frozen plasma vs no treatment
Frequency of adverse events · People undergoing stem cell transplants with malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Antithrombin III plus heparin vs heparin alone
Overall survival · People undergoing stem cell transplant with malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Antithrombin III plus heparin vs heparin alone
All‐cause mortality at 100 days post‐transplant · People undergoing stem cell transplant with malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Antithrombin III plus heparin vs heparin alone
Quality of life · People undergoing stem cell transplant with malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Heparin vs low molecular weight heparin
Overall survival · Patients undergoing stem cell transplant with malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Heparin vs low molecular weight heparin
All‐cause mortality at 100 days post‐transplant · Patients undergoing stem cell transplant with malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Heparin vs low molecular weight heparin
Quality of life · Patients undergoing stem cell transplant with malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Ursodeoxycholic acid vs placebo or no treatment
Quality of life · People undergoing stem cell transplant with a variety of malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Heparin vs prostaglandin E1
Overall survival · Patients undergoing stem cell transplant with malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Heparin vs prostaglandin E1
All‐cause mortality at 100 days post‐transplant · Patients undergoing stem cell transplant with malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Heparin vs prostaglandin E1
Quality of life · Patients undergoing stem cell transplant with malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Low molecular weight heparin vs prostaglandin E1
Overall survival · People undergoing stem cell transplant with malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Low molecular weight heparin vs prostaglandin E1
All‐cause mortality at 100 days post‐transplant · People undergoing stem cell transplant with malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Low molecular weight heparin vs prostaglandin E1
Quality of life · People undergoing stem cell transplant with malignant and non‐malignant diseases
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane
no estimate extractedNRNo studies
Long‐stored ('older') PRBC (≥ 21 days of storage) vs short‐stored (fresh) PRBC (< 21 days of storage)
Transfusion‐related acute lung injury ‐ not measured · patients requiring blood transfusion (children with malaria and adults with a traumatic injury)
Prolonged storage of packed red blood cells for blood transfusion (2015) · Cochrane
no estimate extractedNRNo studies
Long‐stored ('older') PRBC (≥ 21 days of storage) vs short‐stored (fresh) PRBC (< 21 days of storage)
Postoperative infections ‐ not measured · patients requiring blood transfusion (children with malaria and adults with a traumatic injury)
Prolonged storage of packed red blood cells for blood transfusion (2015) · Cochrane
no estimate extractedNRNo studies
Long‐stored ('older') PRBC (≥ 21 days of storage) vs short‐stored (fresh) PRBC (< 21 days of storage)
Post‐injury coagulopathy ‐ not measured · patients requiring blood transfusion (children with malaria and adults with a traumatic injury)
Prolonged storage of packed red blood cells for blood transfusion (2015) · Cochrane
no estimate extractedNRNo studies
Long‐stored ('older') PRBC (≥ 21 days of storage) vs short‐stored (fresh) PRBC (< 21 days of storage)
Multiple organ failure post‐injury ‐ not measured · patients requiring blood transfusion (children with malaria and adults with a traumatic injury)
Prolonged storage of packed red blood cells for blood transfusion (2015) · Cochrane
no estimate extractedNRNo studies
Long‐stored ('older') PRBC (≥ 21 days of storage) vs short‐stored (fresh) PRBC (< 21 days of storage)
Adverse event (Hyperkalaemia) ‐ not measured · patients requiring blood transfusion (children with malaria and adults with a traumatic injury)
Prolonged storage of packed red blood cells for blood transfusion (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Change in other outcomes · 106 participants with primary brain tumour
Multidisciplinary rehabilitation after primary brain tumour treatment (2015) · Cochrane
no estimate extractedNRNo studies
Tramadol vs fentanyl
Number of patients with moderate to severe pain (PACU) · children undergoing surgery
Tramadol for postoperative pain treatment in children (2015) · Cochrane
no estimate extractedNRNo studies
Tramadol vs morphine
Number of patients with moderate to severe pain (PACU) · children undergoing surgery
Tramadol for postoperative pain treatment in children (2015) · Cochrane
no estimate extractedNRNo studies
Oral antibiotics vs IV antibiotics
Time to next exacerbation · people with cystic fibrosis experiencing a pulmonary exacerbation
Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis (2015) · Cochrane
no estimate extractedNRNo studies
Oral antibiotics vs IV antibiotics
Quality of life · people with cystic fibrosis experiencing a pulmonary exacerbation
Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis (2015) · Cochrane
no estimate extractedNRNo studies
Single vs combination IV antibiotics
Quality of life · people with cystic fibrosis experiencing a pulmonary exacerbation
Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis (2015) · Cochrane
no estimate extractedNRNo studies
Nebulised antibiotics vs IV antibiotics
Time to next exacerbation · people with cystic fibrosis experiencing a pulmonary exacerbation
Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis (2015) · Cochrane
no estimate extractedNRNo studies