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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

196 questions in 33 reviews · Urology

current versions
No studies 196 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
NBI + WLC TURBT vs WLC TURBT
Time to disease progression · transurethral resection of bladder tumors in people with suspected or diagnosed non‐muscle invasive bladder cancer
Narrow band imaging versus white light cystoscopy alone for transurethral resection of non‐muscle invasive… (2022) · Cochrane
no estimate extractedNRNo studies
NBI + WLC TURBT vs WLC TURBT
Time to death from bladder cancer · transurethral resection of bladder tumors in people with suspected or diagnosed non‐muscle invasive bladder cancer
Narrow band imaging versus white light cystoscopy alone for transurethral resection of non‐muscle invasive… (2022) · Cochrane
no estimate extractedNRNo studies
Gemcitabine vs mitomycin
Time to death from bladder cancer · participants with non‐muscle invasive bladder cancer1 (93 men, 16 women)Country: Italy
Intravesical gemcitabine for non‐muscle invasive bladder cancer (2021) · Cochrane
no estimate extractedNRNo studies
Gemcitabine vs mitomycin
Time to death from any cause · participants with non‐muscle invasive bladder cancer1 (93 men, 16 women)Country: Italy
Intravesical gemcitabine for non‐muscle invasive bladder cancer (2021) · Cochrane
no estimate extractedNRNo studies
Gemcitabine vs mitomycin
Disease‐specific quality of life · participants with non‐muscle invasive bladder cancer1 (93 men, 16 women)Country: Italy
Intravesical gemcitabine for non‐muscle invasive bladder cancer (2021) · Cochrane
no estimate extractedNRNo studies
Gemcitabine vs BCG
Time to death from any cause · participants with recurrent (1‐course BCG failure) high‐risk non‐muscle invasive bladder cancer (49 men, 31…
Intravesical gemcitabine for non‐muscle invasive bladder cancer (2021) · Cochrane
no estimate extractedNRNo studies
Gemcitabine vs BCG
Disease‐specific quality of life · participants with recurrent (1‐course BCG failure) high‐risk non‐muscle invasive bladder cancer (49 men, 31…
Intravesical gemcitabine for non‐muscle invasive bladder cancer (2021) · Cochrane
no estimate extractedNRNo studies
Gemcitabine vs saline
Disease‐specific quality of life · participants with non‐muscle invasive bladder cancer (607 men, 127 women)Country: Germany, Turkey, and the US
Intravesical gemcitabine for non‐muscle invasive bladder cancer (2021) · Cochrane
no estimate extractedNRNo studies
Combination therapy vs anticholinergics
Surgical intervention – not reported · men with lower urinary tract symptoms related to benign prostatic obstruction
Anticholinergics combined with alpha‐blockers for treating lower urinary tract symptoms related to benign… (2021) · Cochrane
no estimate extractedNRNo studies
Combination therapy vs placebo
Surgical intervention – not reported · men with lower urinary tract symptoms related to benign prostatic obstruction
Anticholinergics combined with alpha‐blockers for treating lower urinary tract symptoms related to benign… (2021) · Cochrane
no estimate extractedNRNo studies
Degarelix vs standard androgen suppression therapy
Overall survival · hormone‐sensitive prostate cancer
Degarelix for treating advanced hormone‐sensitive prostate cancer (2021) · Cochrane
no estimate extractedNRNo studies
Degarelix vs standard androgen suppression therapy
Cancer‐specific survival  · hormone‐sensitive prostate cancer
Degarelix for treating advanced hormone‐sensitive prostate cancer (2021) · Cochrane
no estimate extractedNRNo studies
Ginseng vs placebo
Quality of life ‐ not measured · men with ED
Ginseng for erectile dysfunction (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
TUMT (mixed estimate) · men with moderate to severe lower urinary symptoms due to benign prostatic hyperplasia Interventions: minimally…
Minimally invasive treatments for lower urinary tract symptoms in men with benign prostatic hyperplasia: a… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
TIND (indirect estimate) · men with moderate to severe lower urinary symptoms due to benign prostatic hyperplasia Interventions: minimally…
Minimally invasive treatments for lower urinary tract symptoms in men with benign prostatic hyperplasia: a… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
PAE (mixed estimate) · men with moderate to severe lower urinary symptoms due to benign prostatic hyperplasia Interventions: minimally…
Minimally invasive treatments for lower urinary tract symptoms in men with benign prostatic hyperplasia: a… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
TUMT · men with moderate to severe lower urinary symptoms due to benign prostatic hyperplasia Interventions: minimally…
Minimally invasive treatments for lower urinary tract symptoms in men with benign prostatic hyperplasia: a… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
TUMT (mixed estimate) · men with moderate to severe lower urinary symptoms due to benign prostatic hyperplasia Interventions: minimally…
Minimally invasive treatments for lower urinary tract symptoms in men with benign prostatic hyperplasia: a… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
PAE (mixed estimate) · men with moderate to severe lower urinary symptoms due to benign prostatic hyperplasia Interventions: minimally…
Minimally invasive treatments for lower urinary tract symptoms in men with benign prostatic hyperplasia: a… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
CRFWVT (Rezūm) (pairwise) · men with moderate to severe lower urinary symptoms due to benign prostatic hyperplasia Interventions: minimally…
Minimally invasive treatments for lower urinary tract symptoms in men with benign prostatic hyperplasia: a… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
TIND (pairwise) · men with moderate to severe lower urinary symptoms due to benign prostatic hyperplasia Interventions: minimally…
Minimally invasive treatments for lower urinary tract symptoms in men with benign prostatic hyperplasia: a… (2021) · Cochrane
no estimate extractedNRNo studies
Blue light vs white light
Surgical complications, non‐serious (up to 90 days; MCID 5%) · people with non‐muscle invasive bladder cancer
Blue versus white light for transurethral resection of non‐muscle invasive bladder cancer (2021) · Cochrane
no estimate extractedNRNo studies
Sunitinib vs avelumab + axitinib (targeted agent versus immunotherapy + targeted agent)
Health‐related quality of life4 · Treatment‐naïve metastatic renal cell carcinoma (clear cell type)
Targeted therapy for metastatic renal cell carcinoma (2020) · Cochrane
no estimate extractedNRNo studies
Sunitinib vs pembrolizumab + axitinib (targeted agent versus immunotherapy + targeted agent)
Health‐related quality of life4 · Treatment‐naïve metastatic renal cell carcinoma (clear cell type)
Targeted therapy for metastatic renal cell carcinoma (2020) · Cochrane
no estimate extractedNRNo studies
Sunitinib vs IMA901 + sunitinib (targeted agent versus tumour vaccine + targeted agent)
Health‐related quality of life6 · Treatment‐naïve metastatic renal cell carcinoma (clear cell type)
Targeted therapy for metastatic renal cell carcinoma (2020) · Cochrane
no estimate extractedNRNo studies
Sorafenib vs sunitinib (targeted agent versus targeted agent)
Health‐related quality of life5 · Treatment‐naïve metastatic renal cell carcinoma (any cell type)
Targeted therapy for metastatic renal cell carcinoma (2020) · Cochrane
no estimate extractedNRNo studies
Bevacizumab + IFN vs IFN (+ placebo) (targeted agent + classic immunotherapy versus classic immunotherapy)
Health‐related quality of life3 · Treatment‐naïve metastatic renal cell carcinoma (clear cell type)
Targeted therapy for metastatic renal cell carcinoma (2020) · Cochrane
no estimate extractedNRNo studies
Temsirolimus + bevacizumab vs bevacizumab + IFN‐α (targeted agent + targeted agent versus targeted agent + classic immunotherapy)
Health‐related quality of life3 · Treatment‐naïve metastatic renal cell carcinoma (any cell type [80% clear cell])
Targeted therapy for metastatic renal cell carcinoma (2020) · Cochrane
no estimate extractedNRNo studies
Everolimus + bevacizumab vs IFN α‐2a + bevacizumab (targeted agent + targeted agent versus targeted agent + classic immunotherapy)
Health‐related quality of life5 · Treatment‐naïve metastatic renal cell carcinoma (any cell type)
Targeted therapy for metastatic renal cell carcinoma (2020) · Cochrane
no estimate extractedNRNo studies
Alpha‐blocker as adjuvant medical expulsive therapy plus usual care vs usual care
Quality of life · adults with renal and ureteral stones undergoing shock wave lithotripsy
Alpha‐blockers after shock wave lithotripsy for renal or ureteral stones in adults (2020) · Cochrane
no estimate extractedNRNo studies
Branch chain amino acids vs dextrose
Length of hospital stay – not assessed
Perioperative nutrition for the treatment of bladder cancer by radical cystectomy (2019) · Cochrane
no estimate extractedNRNo studies
Branch chain amino acids vs dextrose
Mortality – not assessed
Perioperative nutrition for the treatment of bladder cancer by radical cystectomy (2019) · Cochrane
no estimate extractedNRNo studies
Preoperative oral nutritional support vs normal diet
Length of hospital stay – not measured
Perioperative nutrition for the treatment of bladder cancer by radical cystectomy (2019) · Cochrane
no estimate extractedNRNo studies
Percutaneous nephrolithotripsy vs tubeless mini‐percutaneous nephrolithotripsy
Serious adverse events or complications of treatment — not reported
Medical and surgical interventions for the treatment of urinary stones in children (2019) · Cochrane
no estimate extractedNRNo studies
Alpha‐blockers vs placebo with/without analgesics
Hospital stay — not reported
Medical and surgical interventions for the treatment of urinary stones in children (2019) · Cochrane
no estimate extractedNRNo studies
Shock wave lithotripsy vs dissolution therapy
Hospital stay — not reported
Medical and surgical interventions for the treatment of urinary stones in children (2019) · Cochrane
no estimate extractedNRNo studies
Slow shock wave lithotripsy vs rapid shock wave lithotripsy
Hospital stay — not reported
Medical and surgical interventions for the treatment of urinary stones in children (2019) · Cochrane
no estimate extractedNRNo studies
5‐alpha reductase inhibitors vs placebo
Sexual dysfunction ‐ not reported · men with chronic prostatitis/chronic pelvic pain syndrome
Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome (2019) · Cochrane
no estimate extractedNRNo studies
5‐alpha reductase inhibitors vs placebo
Quality of life ‐ not reported · men with chronic prostatitis/chronic pelvic pain syndrome
Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome (2019) · Cochrane
no estimate extractedNRNo studies
5‐alpha reductase inhibitors vs placebo
Anxiety and depression ‐ not reported · men with chronic prostatitis/chronic pelvic pain syndrome
Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome (2019) · Cochrane
no estimate extractedNRNo studies
Antibiotic therapy vs placebo
Anxiety and depression ‐ not reported · men with chronic prostatitis/chronic pelvic pain syndrome
Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome (2019) · Cochrane
no estimate extractedNRNo studies
Anti‐inflammatories vs control
Sexual dysfunction ‐ not reported · men with chronic prostatitis/chronic pelvic pain syndrome
Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome (2019) · Cochrane
no estimate extractedNRNo studies
Anti‐inflammatories vs control
Quality of life ‐ not reported · men with chronic prostatitis/chronic pelvic pain syndrome
Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome (2019) · Cochrane
no estimate extractedNRNo studies
Anti‐inflammatories vs control
Anxiety and depression ‐ not reported · men with chronic prostatitis/chronic pelvic pain syndrome
Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome (2019) · Cochrane
no estimate extractedNRNo studies
Phytotherapy vs placebo or other agents
Quality of life ‐ not reported · men with chronic prostatitis/chronic pelvic pain syndrome
Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome (2019) · Cochrane
no estimate extractedNRNo studies
Phytotherapy vs placebo or other agents
Anxiety and depression ‐ not reported · men with chronic prostatitis/chronic pelvic pain syndrome
Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome (2019) · Cochrane
no estimate extractedNRNo studies
Botulinum toxin A vs placebo
Sexual dysfunction ‐ not reported · men with chronic prostatitis/chronic pelvic pain syndrome
Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome (2019) · Cochrane
no estimate extractedNRNo studies
Botulinum toxin A vs placebo
Quality of life ‐ not reported · men with chronic prostatitis/chronic pelvic pain syndrome
Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome (2019) · Cochrane
no estimate extractedNRNo studies
Botulinum toxin A vs placebo
Anxiety and depression ‐ not reported · men with chronic prostatitis/chronic pelvic pain syndrome
Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome (2019) · Cochrane
no estimate extractedNRNo studies
Allopurinol vs placebo
Sexual dysfunction ‐ not reported · men with chronic prostatitis/chronic pelvic pain syndrome
Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome (2019) · Cochrane
no estimate extractedNRNo studies