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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

125 questions in 24 reviews · Injuries

current versions
No studies 125 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Intervention NR
Occupational effects · people with severe frostbite injuries
Interventions for frostbite injuries (2020) · Cochrane
no estimate extractedNRNo studies
Intravenous iron therapy vs oral iron therapy
Proportion of participants who received a blood transfusion · people with preoperative anaemia awaiting major surgery
Iron therapy for preoperative anaemia (2019) · Cochrane
no estimate extractedNRNo studies
Intravenous iron therapy vs oral iron therapy
Any validated measure of quality of life · people with preoperative anaemia awaiting major surgery
Iron therapy for preoperative anaemia (2019) · Cochrane
no estimate extractedNRNo studies
Intravenous iron therapy vs oral iron therapy
Haemoglobin levels post‐treatment and surgery (g/dL) · people with preoperative anaemia awaiting major surgery
Iron therapy for preoperative anaemia (2019) · Cochrane
no estimate extractedNRNo studies
Intravenous iron vs placebo
Bacterial infection · non‐anaemic, iron‐deficient adults
Intravenous iron therapy for non‐anaemic, iron‐deficient adults (2019) · Cochrane
no estimate extractedNRNo studies
Intravenous iron vs placebo
Serious adverse events · non‐anaemic, iron‐deficient adults
Intravenous iron therapy for non‐anaemic, iron‐deficient adults (2019) · Cochrane
no estimate extractedNRNo studies
Dextrans vs crystalloid
Renal replacement therapy
Colloids versus crystalloids for fluid resuscitation in critically ill people (2018) · Cochrane
no estimate extractedNRNo studies
Dextrans vs crystalloid
Adverse events
Colloids versus crystalloids for fluid resuscitation in critically ill people (2018) · Cochrane
no estimate extractedNRNo studies
Gelatins vs crystalloid
Renal replacement therapy
Colloids versus crystalloids for fluid resuscitation in critically ill people (2018) · Cochrane
no estimate extractedNRNo studies
SDAC vs no intervention
Incidence of mortality · first aid in patients with acute oral poisoning (paracetamol or not specified)
First aid interventions by laypeople for acute oral poisoning (2018) · Cochrane
no estimate extractedNRNo studies
MDAC + hospital intervention vs SDAC + hospital intervention
Incidence of hospitalization · first aid in patients with acute oral poisoning (carbamazepine, yellow oleander, or combinations of different drugs)
First aid interventions by laypeople for acute oral poisoning (2018) · Cochrane
no estimate extractedNRNo studies
SDAC vs syrup of ipecac
Incidence of mortality · first aid in patients with acute oral poisoning (anti‐inflammatory drugs, analgesics or psychotropic drugs)
First aid interventions by laypeople for acute oral poisoning (2018) · Cochrane
no estimate extractedNRNo studies
SDAC vs syrup of ipecac
Duration of toxic symptoms · first aid in patients with acute oral poisoning (anti‐inflammatory drugs, analgesics or psychotropic drugs)
First aid interventions by laypeople for acute oral poisoning (2018) · Cochrane
no estimate extractedNRNo studies
SDAC vs syrup of ipecac
Drug absorption · first aid in patients with acute oral poisoning (anti‐inflammatory drugs, analgesics or psychotropic drugs)
First aid interventions by laypeople for acute oral poisoning (2018) · Cochrane
no estimate extractedNRNo studies
SDAC vs syrup of ipecac
Incidence of hospitalization · first aid in patients with acute oral poisoning (anti‐inflammatory drugs, analgesics or psychotropic drugs)
First aid interventions by laypeople for acute oral poisoning (2018) · Cochrane
no estimate extractedNRNo studies
SDAC vs syrup of ipecac
Incidence of ICU admission · first aid in patients with acute oral poisoning (anti‐inflammatory drugs, analgesics or psychotropic drugs)
First aid interventions by laypeople for acute oral poisoning (2018) · Cochrane
no estimate extractedNRNo studies
MDAC + hospital intervention vs hospital intervention
Incidence of hospitalization · first aid in patients with acute oral poisoning (benzodiazepines, yellow oleander or combinations of different drugs)
First aid interventions by laypeople for acute oral poisoning (2018) · Cochrane
no estimate extractedNRNo studies
MDAC + hospital intervention vs hospital intervention
Incidence of ICU admission · first aid in patients with acute oral poisoning (benzodiazepines, yellow oleander or combinations of different drugs)
First aid interventions by laypeople for acute oral poisoning (2018) · Cochrane
no estimate extractedNRNo studies
Syrup of ipecac vs no intervention
Incidence of mortality · first aid in patients with acute oral poisoning (toxic berries)
First aid interventions by laypeople for acute oral poisoning (2018) · Cochrane
no estimate extractedNRNo studies
Syrup of ipecac vs no intervention
Incidence and severity of symptoms of poisoning · first aid in patients with acute oral poisoning (toxic berries)
First aid interventions by laypeople for acute oral poisoning (2018) · Cochrane
no estimate extractedNRNo studies
Syrup of ipecac vs no intervention
Duration of toxic symptoms · first aid in patients with acute oral poisoning (toxic berries)
First aid interventions by laypeople for acute oral poisoning (2018) · Cochrane
no estimate extractedNRNo studies
SDAC vs no intervention
Duration of toxic symptoms · first aid in patients with acute oral poisoning (paracetamol or not specified)
First aid interventions by laypeople for acute oral poisoning (2018) · Cochrane
no estimate extractedNRNo studies
Syrup of ipecac vs no intervention
Drug absorption · first aid in patients with acute oral poisoning (toxic berries)
First aid interventions by laypeople for acute oral poisoning (2018) · Cochrane
no estimate extractedNRNo studies
Syrup of ipecac vs no intervention
ICU admission · first aid in patients with acute oral poisoning (toxic berries)
First aid interventions by laypeople for acute oral poisoning (2018) · Cochrane
no estimate extractedNRNo studies
SDAC vs no intervention
Drug absorption · first aid in patients with acute oral poisoning (paracetamol or not specified)
First aid interventions by laypeople for acute oral poisoning (2018) · Cochrane
no estimate extractedNRNo studies
SDAC vs no intervention
Incidence of hospitalization · first aid in patients with acute oral poisoning (paracetamol or not specified)
First aid interventions by laypeople for acute oral poisoning (2018) · Cochrane
no estimate extractedNRNo studies
DDAVP vs placebo or standard care: platelet dysfunction subgroup
Quality of life · participants with platelet dysfunction undergoing surgery
Desmopressin use for minimising perioperative blood transfusion (2017) · Cochrane
no estimate extractedNRNo studies
DDAVP vs tranexamic acid
All‐cause mortality · participants undergoing surgery
Desmopressin use for minimising perioperative blood transfusion (2017) · Cochrane
no estimate extractedNRNo studies
DDAVP vs tranexamic acid
Quality of life · participants undergoing surgery
Desmopressin use for minimising perioperative blood transfusion (2017) · Cochrane
no estimate extractedNRNo studies
DDAVP vs aprotinin
Red cell volume transfused (total) · participants undergoing surgery
Desmopressin use for minimising perioperative blood transfusion (2017) · Cochrane
no estimate extractedNRNo studies
DDAVP vs aprotinin
Blood loss (total) · participants undergoing surgery
Desmopressin use for minimising perioperative blood transfusion (2017) · Cochrane
no estimate extractedNRNo studies
DDAVP vs aprotinin
Quality of life · participants undergoing surgery
Desmopressin use for minimising perioperative blood transfusion (2017) · Cochrane
no estimate extractedNRNo studies
DDAVP vs placebo or standard care
Quality of life · participants undergoing surgery
Desmopressin use for minimising perioperative blood transfusion (2017) · Cochrane
no estimate extractedNRNo studies
Botulinum toxin A (with and without casting) vs placebo (with and without casting)
Sensory functions and pain · adults with traumatic brain injury with spasticity in their arms (1 study) or calves (1 study)
Interventions for managing skeletal muscle spasticity following traumatic brain injury (2017) · Cochrane
no estimate extractedNRNo studies
Botulinum toxin A (with and without casting) vs placebo (with and without casting)
General tasks and demands · adults with traumatic brain injury with spasticity in their arms (1 study) or calves (1 study)
Interventions for managing skeletal muscle spasticity following traumatic brain injury (2017) · Cochrane
no estimate extractedNRNo studies
Botulinum toxin A (with and without casting) vs placebo (with and without casting)
Mobility · adults with traumatic brain injury with spasticity in their arms (1 study) or calves (1 study)
Interventions for managing skeletal muscle spasticity following traumatic brain injury (2017) · Cochrane
no estimate extractedNRNo studies
Botulinum toxin A (with and without casting) vs placebo (with and without casting)
Self‐care · adults with traumatic brain injury with spasticity in their arms (1 study) or calves (1 study)
Interventions for managing skeletal muscle spasticity following traumatic brain injury (2017) · Cochrane
no estimate extractedNRNo studies
Pseudoelastic orthosis vs traditional (static) splint
Sensory functions and pain · children/young people aged 4‐18 years with traumatic brain injury and with 'mild to severe spastic tetraparesis'…
Interventions for managing skeletal muscle spasticity following traumatic brain injury (2017) · Cochrane
no estimate extractedNRNo studies
Pseudoelastic orthosis vs traditional (static) splint
General tasks and demands · children/young people aged 4‐18 years with traumatic brain injury and with 'mild to severe spastic tetraparesis'…
Interventions for managing skeletal muscle spasticity following traumatic brain injury (2017) · Cochrane
no estimate extractedNRNo studies
Pseudoelastic orthosis vs traditional (static) splint
Mobility · children/young people aged 4‐18 years with traumatic brain injury and with 'mild to severe spastic tetraparesis'…
Interventions for managing skeletal muscle spasticity following traumatic brain injury (2017) · Cochrane
no estimate extractedNRNo studies
Pseudoelastic orthosis vs traditional (static) splint
Self‐care · children/young people aged 4‐18 years with traumatic brain injury and with 'mild to severe spastic tetraparesis'…
Interventions for managing skeletal muscle spasticity following traumatic brain injury (2017) · Cochrane
no estimate extractedNRNo studies
Baclofen vs placebo
Sensory functions and pain · adults with traumatic brain injury with spasticity in their arms and legs
Interventions for managing skeletal muscle spasticity following traumatic brain injury (2017) · Cochrane
no estimate extractedNRNo studies
Baclofen vs placebo
General tasks and demands · adults with traumatic brain injury with spasticity in their arms and legs
Interventions for managing skeletal muscle spasticity following traumatic brain injury (2017) · Cochrane
no estimate extractedNRNo studies
Baclofen vs placebo
Mobility · adults with traumatic brain injury with spasticity in their arms and legs
Interventions for managing skeletal muscle spasticity following traumatic brain injury (2017) · Cochrane
no estimate extractedNRNo studies
Baclofen vs placebo
Self‐care · adults with traumatic brain injury with spasticity in their arms and legs
Interventions for managing skeletal muscle spasticity following traumatic brain injury (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Quality of life; Glasgow Coma Score; Disability · people with severe traumatic brain injury (adults and children)
Elevation of the head during intensive care management in people with severe traumatic brain injury (2017) · Cochrane
no estimate extractedNRNo studies
Technological aid vs internet resource
Quality of life ‐ not reported · Children or adolescents with acquired brain injury
Technological aids for the rehabilitation of memory and executive functioning in children and adolescents… (2016) · Cochrane
no estimate extractedNRNo studies
Technological aid vs internet resource
Social functioning ‐ not reported · Children or adolescents with acquired brain injury
Technological aids for the rehabilitation of memory and executive functioning in children and adolescents… (2016) · Cochrane
no estimate extractedNRNo studies
Technological aid vs internet resource
Academic achievement ‐ not reported · Children or adolescents with acquired brain injury
Technological aids for the rehabilitation of memory and executive functioning in children and adolescents… (2016) · Cochrane
no estimate extractedNRNo studies
Technological aid vs internet resource
Adverse events · Children or adolescents with acquired brain injury
Technological aids for the rehabilitation of memory and executive functioning in children and adolescents… (2016) · Cochrane
no estimate extractedNRNo studies