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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
531 questions in 102 reviews · Gynaecology and Fertility
current versionsNo studies 531 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Oral vs vaginal administration of oestradiol and dydrogesterone Reproductive outcomes · women with premature ovarian insufficiency (POI) awaiting oocyte donation Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane | no estimate extracted | NR | No studies |
Oral vs vaginal administration of oestradiol and dydrogesterone Adverse events · women with premature ovarian insufficiency (POI) awaiting oocyte donation Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane | no estimate extracted | NR | No studies |
Conjugated oral oestrogens vs transdermal 17ß‐estradiol Endometrial histology · girls with Turner syndrome who were treated with prepubertal growth hormone Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane | no estimate extracted | NR | No studies |
Conjugated oral oestrogens vs transdermal 17ß‐estradiol Uterine perfusion · girls with Turner syndrome who were treated with prepubertal growth hormone Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane | no estimate extracted | NR | No studies |
Conjugated oral oestrogens vs transdermal 17ß‐estradiol Reproductive outcomes · girls with Turner syndrome who were treated with prepubertal growth hormone Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane | no estimate extracted | NR | No studies |
Conjugated oral oestrogens vs transdermal 17ß‐estradiol Adverse events · girls with Turner syndrome who were treated with prepubertal growth hormone Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane | no estimate extracted | NR | No studies |
Low vs high 17ß‐oestradiol dose Endometrial thickness · young women with Turner syndrome who have completed pubertal induction Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane | no estimate extracted | NR | No studies |
Letrozole vs laparoscopic ovarian drilling Ovarian hyperstimulation syndrome rate · infertile women with polycystic ovary syndrome Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome (2022) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Live birth or ongoing pregnancy: early (EFP) vs late (LFP) follicular phase · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI) Endometrial injury for pregnancy following sexual intercourse or intrauterine insemination (2022) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Live birth or ongoing pregnancy: prior cycle vs IUI cycle · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI) Endometrial injury for pregnancy following sexual intercourse or intrauterine insemination (2022) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Pain during the procedure · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI) Endometrial injury for pregnancy following sexual intercourse or intrauterine insemination (2022) · Cochrane | no estimate extracted | NR | No studies |
Progesterone vs no treatment or placebo (route of progesterone administration) Outcomes* · women trying to conceive by intrauterine insemination Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse (2022) · Cochrane | no estimate extracted | NR | No studies |
Progesterone vs placebo/no treatment Adverse events, OHSS, preterm delivery, congenital anomaly · women with gonadotropin stimulation Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse (2022) · Cochrane | no estimate extracted | NR | No studies |
Progesterone vs placebo/no treatment Live birth rate · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse (2022) · Cochrane | no estimate extracted | NR | No studies |
Progesterone vs placebo/no treatment Adverse events, OHSS, preterm delivery, congenital anomaly · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse (2022) · Cochrane | no estimate extracted | NR | No studies |
Progesterone vs placebo/no treatment Adverse events, OHSS, preterm delivery, congenital anomaly · women with oral (clomiphene citrate or letrozole) stimulation Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse (2022) · Cochrane | no estimate extracted | NR | No studies |
Intramuscular (IM) progesterone vs vaginal progesterone Live birth rate · women trying to conceive by intrauterine insemination Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse (2022) · Cochrane | no estimate extracted | NR | No studies |
Intramuscular (IM) progesterone vs vaginal progesterone Multiple pregnancy rate · women trying to conceive by intrauterine insemination Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse (2022) · Cochrane | no estimate extracted | NR | No studies |
Intramuscular (IM) progesterone vs vaginal progesterone OHSS, preterm delivery, congenital anomaly · women trying to conceive by intrauterine insemination Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse (2022) · Cochrane | no estimate extracted | NR | No studies |
Oral progesterone vs vaginal progesterone Live birth rate · women trying to conceive by intrauterine insemination Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse (2022) · Cochrane | no estimate extracted | NR | No studies |
Oral progesterone vs vaginal progesterone Multiple pregnancy rate · women trying to conceive by intrauterine insemination Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse (2022) · Cochrane | no estimate extracted | NR | No studies |
Oral progesterone vs vaginal progesterone Adverse events, OHSS, preterm delivery, congenital anomaly · women trying to conceive by intrauterine insemination Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse (2022) · Cochrane | no estimate extracted | NR | No studies |
Subcutaneous (Sc) gonadotropin‐releasing hormone (GnRH) agonist vs placebo/no treatment Live birth · women trying to conceive by intrauterine insemination Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse (2022) · Cochrane | no estimate extracted | NR | No studies |
Subcutaneous (Sc) gonadotropin‐releasing hormone (GnRH) agonist vs placebo/no treatment Adverse events, OHSS, preterm delivery, congenital anomaly · women trying to conceive by intrauterine insemination Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse (2022) · Cochrane | no estimate extracted | NR | No studies |
Progesterone vs no treatment or placebo (route of progesterone administration) Adverse events, OHSS, preterm delivery, congenital anomaly · women trying to conceive by intrauterine insemination Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse (2022) · Cochrane | no estimate extracted | NR | No studies |
Surgical treatment vs radiological treatment Quality of life · Varicoceles in subfertile men Surgical or radiological treatment for varicoceles in subfertile men (2021) · Cochrane | no estimate extracted | NR | No studies |
Surgical treatment vs other surgical treatment Live birth · Varicoceles in subfertile men Surgical or radiological treatment for varicoceles in subfertile men (2021) · Cochrane | no estimate extracted | NR | No studies |
Surgical treatment vs other surgical treatment Adverse events · Varicoceles in subfertile men Surgical or radiological treatment for varicoceles in subfertile men (2021) · Cochrane | no estimate extracted | NR | No studies |
Surgical treatment vs other surgical treatment Pregnancy · Varicoceles in subfertile men Surgical or radiological treatment for varicoceles in subfertile men (2021) · Cochrane | no estimate extracted | NR | No studies |
Surgical treatment vs other surgical treatment Varicocele recurrence · Varicoceles in subfertile men Surgical or radiological treatment for varicoceles in subfertile men (2021) · Cochrane | no estimate extracted | NR | No studies |
Surgical treatment vs other surgical treatment Quality of life · Varicoceles in subfertile men Surgical or radiological treatment for varicoceles in subfertile men (2021) · Cochrane | no estimate extracted | NR | No studies |
Radiological treatment vs radiological treatment Live birth · Varicoceles in subfertile men Surgical or radiological treatment for varicoceles in subfertile men (2021) · Cochrane | no estimate extracted | NR | No studies |
Radiological treatment vs radiological treatment Adverse events · Varicoceles in subfertile men Surgical or radiological treatment for varicoceles in subfertile men (2021) · Cochrane | no estimate extracted | NR | No studies |
Radiological treatment vs radiological treatment Pregnancy · Varicoceles in subfertile men Surgical or radiological treatment for varicoceles in subfertile men (2021) · Cochrane | no estimate extracted | NR | No studies |
Varicocele treatment vs non‐surgical, delayed, or no treatment Adverse events · Varicoceles in subfertile men Surgical or radiological treatment for varicoceles in subfertile men (2021) · Cochrane | no estimate extracted | NR | No studies |
Radiological treatment vs radiological treatment Quality of life · Varicoceles in subfertile men Surgical or radiological treatment for varicoceles in subfertile men (2021) · Cochrane | no estimate extracted | NR | No studies |
Varicocele treatment vs non‐surgical, delayed, or no treatment Varicocele recurrence · Varicoceles in subfertile men Surgical or radiological treatment for varicoceles in subfertile men (2021) · Cochrane | no estimate extracted | NR | No studies |
Varicocele treatment vs non‐surgical, delayed, or no treatment Quality of life · Varicoceles in subfertile men Surgical or radiological treatment for varicoceles in subfertile men (2021) · Cochrane | no estimate extracted | NR | No studies |
Postoperative use of LNG‐IUD vs expectant management Overall pain at 12 months  · Patients with symptomatic endometriosis following surgery Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery (2021) · Cochrane | no estimate extracted | NR | No studies |
Postoperative use of LNG‐IUD vs postoperative GnRH‐a Improvement of the most troublesome symptom at 12 months  Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery (2021) · Cochrane | no estimate extracted | NR | No studies |
Postoperative use of LNG‐IUD vs postoperative GnRH‐a Quality of life at 12 months  Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery (2021) · Cochrane | no estimate extracted | NR | No studies |
Postoperative use of LNG‐IUD vs postoperative GnRH‐a Patient satisfaction at 12 months Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery (2021) · Cochrane | no estimate extracted | NR | No studies |
Postoperative use of LNG‐IUD vs expectant management Chronic pelvic pain at 12 months  · Patients with symptomatic endometriosis following surgery Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery (2021) · Cochrane | no estimate extracted | NR | No studies |
Postoperative use of LNG‐IUD vs expectant management Improvement of the most troublesome symptom at 12 months  · Patients with symptomatic endometriosis following surgery Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery (2021) · Cochrane | no estimate extracted | NR | No studies |
Postoperative use of LNG‐IUD vs postoperative GnRH‐a  Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery (2021) · Cochrane | no estimate extracted | NR | No studies |
Postoperative use of LNG‐IUD vs postoperative GnRH‐a Overall pain at 12 months  Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery (2021) · Cochrane | no estimate extracted | NR | No studies |
Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only vs monitoring with TVUS plus serum estradiol Live birth per woman · Women undergoing ovarian stimulation with gonadotrophins in IVF and ICSI procedures Monitoring of stimulated cycles in assisted reproduction (IVF and ICSI) (2021) · Cochrane | no estimate extracted | NR | No studies |
Warm saline vs room temperature saline Quality of hysteroscopic view · women undergoing outpatient hysteroscopy Uterine distension media for outpatient hysteroscopy (2021) · Cochrane | no estimate extracted | NR | No studies |
Chinese herbal medicine (CHM) vs clomiphene Live birth rate · subfertile women with PCOS Chinese herbal medicine for subfertile women with polycystic ovarian syndrome (2021) · Cochrane | no estimate extracted | NR | No studies |
Chinese herbal medicine (CHM) plus laparoscopic ovarian drilling (LOD) vs LOD Live birth · subfertile women with PCOS Chinese herbal medicine for subfertile women with polycystic ovarian syndrome (2021) · Cochrane | no estimate extracted | NR | No studies |