Cochrane · systematic review · CD005072

Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery

Gibbons, T, Georgiou, EX, Cheong, YC, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Gynaecology and Fertility2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
15
current version
GRADE rated
7
No studies
8
Included studies
NR
No studies 8 · 53.3%Ungraded 0 · 0%Very low 7 · 46.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Postoperative use of LNG‐IUD compared to expectant management for symptomatic endometriosis following surgery

Population: Patients with symptomatic endometriosis following surgery
7 questions
OutcomeEffectEvidenceStatus / GRADE
Overall pain at 12 months Â
Postoperative use of LNG‐IUD vs expectant management
no estimate extractedNRNo studies
Chronic pelvic pain at 12 months Â
Postoperative use of LNG‐IUD vs expectant management
no estimate extractedNRNo studies
Dysmenorrhoea at 12 months Â
Postoperative use of LNG‐IUD vs expectant management
no estimate extracted95 participantsVery low
Downgraded: imprecision
Improvement of the most troublesome symptom at 12 months Â
Postoperative use of LNG‐IUD vs expectant management
no estimate extractedNRNo studies
Quality of life at 12 months Â
Postoperative use of LNG‐IUD vs expectant management
no estimate extracted1 study · 55 participantsVery low
Downgraded: imprecision
Patient satisfaction at 12 monthsÂ
Postoperative use of LNG‐IUD vs expectant management
no estimate extracted2 studies · 95 participantsVery low
Downgraded: imprecision
Adverse events Â
Postoperative use of LNG‐IUD vs expectant management
no estimate extracted1 study · 55 participantsVery low
Downgraded: imprecision

Postoperative use of LNG‐IUD compared to postoperative GnRH‐a for symptomatic endometriosis after surgery

8 questions
OutcomeEffectEvidenceStatus / GRADE
Â
Postoperative use of LNG‐IUD vs postoperative GnRH‐a
no estimate extractedNRNo studies
Overall pain at 12 months Â
Postoperative use of LNG‐IUD vs postoperative GnRH‐a
no estimate extractedNRNo studies
Chronic pelvic pain at 12 months Â
Postoperative use of LNG‐IUD vs postoperative GnRH‐a
no estimate extracted1 study · 40 participantsVery low
Downgraded: imprecision
Dysmenorrhoea at 12 months Â
Postoperative use of LNG‐IUD vs postoperative GnRH‐a
no estimate extracted1 study · 18 participantsVery low
Downgraded: imprecision
Improvement of the most troublesome symptom at 12 months Â
Postoperative use of LNG‐IUD vs postoperative GnRH‐a
no estimate extractedNRNo studies
Quality of life at 12 months Â
Postoperative use of LNG‐IUD vs postoperative GnRH‐a
no estimate extractedNRNo studies
Patient satisfaction at 12 monthsÂ
Postoperative use of LNG‐IUD vs postoperative GnRH‐a
no estimate extractedNRNo studies
Adverse events Â
Postoperative use of LNG‐IUD vs postoperative GnRH‐a
no estimate extracted1 study · 40 participantsVery low
Downgraded: imprecision